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Faculty Grant Information

Theodore C. Chan, MD

  • Chan T. San Diego Beacon Community Grant to foster Health Information Technology and Exchange in the San Diego region. Funded by the Office of the National Coordinator of Health Information Technology. 2010-2013. Amount: $15.3 Million. Website
  • Chan, T. Wireless Internet Information System for Medical Response to Disasters (WIISARD), funded by the National Library of Medicine. 2003-2008. Amount: $3,200,000. Website
  • Chan, T. Emergency Department National Alcohol Screening Day, Alcohol Education Project, funded by NIH, grant #1 R03 AA015120-01. 2005. Amount: $25,000.
  • Chan, T. The effect of Taser on Cardiac, Respiratory and Metabolic Physiology in Human Subjects. Funded by the National Institute of Justice, U.S. Department of Justice, 2005-7. UCSD No. 2006-0846; USDOJ Federal Award #98-IJ-CX-0079. Amount: $213,941.49
  • Chan, T. Improving Medical Home and Primary Care Access to the Community Clinics Through the ED (IMPACT-ED). Funded by the Alliance Healthcare Foundation, 2006-7. Alliance Grant #06-3114. Amount: $25,000.
  • Chan, T. Evaluation of the Ventilatory and Respiratory Effects of a Restraint Chair on Human Subjects. Study funded by the Institute for the Prevention of In-Custody Deaths, Inc., 1/1/07 to 12/31/07. Amount: $11,658.00
  • Chan, T. Impact of the State Mandated Nurse-Patient Ratio on ED Crowding, Flow and Patient Care. EMF/ENAF (Emergency Medicine Foundation / Emergency Nurses Association Foundation) Directed Team Grant, ED Overcrowding Research Award, 2007-08. Amount: $50,000.
  • Chan, T. San Diego Safety Net Health Information Exchange. Project funded by Pacificare/United Healthcare, 2008-2011. Amount: $715,000.
  • Chan, T. California ED Diversion Project Evaluation. Funded by the California Healthcare Foundation, 05/2008 to 11/2008. Amount $50,990.
  • Chan T. The Gary and Mary West Geriatric Center of Excellence (West COE): Phase 1 Research Development. Funded by the Gary and Mary West Health Institute, 9/15 – 3/16. Amount: $243,610.

Edward Castillo, PhD

  • Castillo EM. Serial Inebriate Program Evaluation. Funded by the California Program on Access to Care, 2005-2006. Amount: $49,000
  • Castillo EM. California ED Diversion Project Evaluation. Funded by the California Healthcare Foundation, 2008-2008. Amount $50,990.
  • Castillo EM. Literature and Policy Gap Analysis. Funded by the Ministry Community Safety & Correctional Services, Ontario Canada, 2013. Amount: $15,000.
  • Castillo EM. Point-of-Care Testing for Illicit Drugs and Alcohol Intoxication in an Emergency Room. Funded by the National Institute on Drug Abuse through Seacoast Science, Inc., 2013-2015. Amount: $50,163.
  • Castillo EM. Integrating Environmental Data into a PHR for Asthma Patients. Funded by the California Health and Human Services Agency, Office of Health Information Integrity, 2013-2014. Amount: $202,079.
  • Castillo EM. Exploring emergency room physician’s knowledge and attitudes concerning the use of appropriate and safe home care as an alternative to hospital admission. Funded by the Gary and Mary West Health Institute, 2014-2015. Amount: $123,152.
  • Castillo EM. Acute Bacterial Skin and Skin Structure Infection (abSSSI) Practice Pattern Assessment.” Funded by Durata Therapeutics International B.V., 2014-2015. Amount: $15,000.
  • Castillo E. Acute Home Care as an Alternative to Inpatient Admission from the Emergency Department. Funded by the Gary and Mary West Health Institute, 9/15 – 8/16. Amount: $499,125.

Richard F. Clark, MD

  • Clark, R. Maternal and Child Health Bureau / Health Resources and Services Administration (MCHB-HRSA) Incentive Grant (CFDA #93.253), “Resources for Management of Exotic Snakebite,” 02/04- 01/14 -- $298,967
  • Clark, R. Savage Labs, “Retrospective Review of Rattlesnake Bite Patients Treated with CroFab,” 07/05-08 -- $10,000
  • Clark, R. Savage Labs, “Solubility Study of CroFab in Intravenous Fluids,” 06/05-06/06 -- $5000 value of antivenom
  • Clark, R. Bioclone Inc., “Phase 2 Clinical Trial of Aracmyn for Black Widow Spider Envenomation,” 1/06-1/14 -- $10,000
  • Clark, R. Rocky Mountain Poison and Drug Center, “Comparing the safety of Oral v. IV NAC,” 1/06-01/09 -- $3000
  • Clark, R. Rocky Mountain Poison and Drug Center, “Characterization of Repeated Supratherapeutic Ingestion of Acetaminophen in Children: a Retrospective Poison Center Study,” 10/06-01/08 -- $500
  • Principal Investigator – Bioclone, Inc., “A Comparison of Anavip® [Crotalinae (pit viper) equine immune F(ab)2] and CroFab® (Crotalidae Polyvalent Immune Fab, ovine) in the Treatment of Patients with Crotalinae Envenomation: A Randomized, Prospective, Blinded, Controlled, Comparative, Multicenter Study,” 7/08-01/15 -- $10,000.
  • Principal Investigator – Cumberland Pharmaceuticals, Inc., “A Multi-center, Double-blind, Randomized, Controlled Study to Determine the Efficacy and Safety of a New Formulation of Acetylcysteine Injection,” 10/10-01/15 -- $10,000

Kama Z. Guluma, MD

  • Guluma, K. “Clinical trial of the safety and feasibility of induced therapeutic hypothermia with thrombolytic therapy in the setting of acute stroke”. University of California, San Diego. 2003 – Present. (NIH P50N5044148).
  • Guluma, K. “Acute thrombomodulatory effects of neurotrophic growth factors in acute stroke”. University of California San Diego. 2003 – Present. (NIH 5-K12-AG000975-05).
  • Guluma, K. “An assessment of cortical spreading depression and its cerebral metabolic effects following experimental traumatic brain injury”. University of Michigan. 1999 – 2001.

David A. Guss, MD

  • Guss, D. REDHOT, Phase II. Funded by Biosite Diagnostic. 2004-2007. $46,400.
  • Guss, D. C1 Inhibitor in Hereditary Angioedema. 2006-2008. $105, 967

Irving “Jake” Jacoby, MD

  • Jacoby, I. “Hospital Bed Surge Capacity in San Diego County”. Awarded June 2003 to County of San Diego, Dept of Health and Human Services, Division of Emergency Preparedness and Disaster Medical Response. 2003 – Present. ($51,150).
  • Jacoby, I. “Hospital Bed Surge Capacity Training Program for Hospitals in San Diego County”. County of San Diego Dept of Health and Human Services, Division of Emergency Preparedness and Disaster Medical Response. 2004 – Present. ($45,000).

James P. Killeen, MD

  • Killeen, J. “Wireless Internet Information System for Medical Response in Disasters”. National Institute of Health in junction with University of California. 2003 – 2006. ($4.1 million).
  • Killeen, J. “Emergency Department Crowding & Safety Net Assessment”. Urgent Matters Program, Robert Wood Johnson Foundation. 2004 – 2005. (Amount: $150,000).
  • Killeen, J. “Improving Medical Home and Primary Care Access to theCommunity
  • Clinics Through the Emergency Department (IMPACT ED)”. AllianceHealthcare Grant, 2006 – present. (Amount: $25,000).
  • Killeen, J. “Multi-Center Study of the Impact of Nurse-Patient Ratios on Emergency Department Overcrowding”. EMF Grant. 2007 – Present. (Amount: $50,000).
  • Killeen, J. “San Diego Safety Net Health Information Exchange.” Pacificare/United Healthcare. 2008-2011. (Amount: $715,000).
  • Killeen, J. "San Diego Safety Net Connect (Safety Net Connect)”. San Diego County. 2008-2010. (Amount: $5,100,000)
  • Co-Principal Investigator with Dr. Chan San Diego Beacon Community Grant to foster Health Information Technology and Exchange in the San Diego region. Funded by the Office of the National Coordinator of Health Information Technology. 2010-2013. Amount: $15.3 Million.
  • Co-Principal Investigator with Dr. Chan The Gary and Mary West Geriatric Center of Excellence (West COE): Phase 1 Research Development. Funded by the Gary and Mary West Health Institute, 9/15 – 3/16. Amount: $243,610.
  • Co-Principal Investigator with Dr. Edward M. Castillo. Acute Home Care as an Alternative to Inpatient Admission from the Emergency Department. Funded by the Gary and Mary West Health Institute, 9/15 – 8/16. Amount: $499,125.
  • Co-Principal Investigator with Dr. Edward M. Castillo. Exploring emergency room physician’s knowledge and attitudes concerning the use of appropriate and safe home care as an alternative to hospital admission. Funded by the Gary and Mary West Health Institute, 2014-2015. Amount: $123,152.
  • Co-Principal Investigator with Dr. Edward M. Castillo. Integrating Environmental Data into a PHR for Asthma Patients. Funded by the California Health and Human Services Agency, Office of Health Information Integrity, 2013-2014. Amount: $202,079.
  • Co-Principal Investigator with Dr. Edward M. Castillo, for study entitled, "Mitigating Legal Risk in the Emergency Department: A UC Health System Wide Collaboration" funded by University of California Office of the President, Division of Health Sciences and Services, Center for Health Quality and Innovation. Amount: $264,465

Binh T. Ly, MD

  • Ly B, UCSD Academic Senate Committee on Research Grant, from February 2001 through March 2002, $10,000.
  • Ly B, Co-Investigator, “GHB Abuse: Motivations, Risk Factors and Medical Consequences” - California Poison Control System - Funded by National Institute on Drug Abuse (NIDA), from July 2003 through April 2007, $27,589.
  • Ly B, Co-Investigator, “Poison Control Stabilization and Enhancement Program” - Funded by Health Resources & Services Administration (HRSA), from September 2001 through August 2010, $625,120.

Christian M. Sloane, MD

  • Sloane, C. The effect of Taser on Cardiac, Respiratory and Metabolic Physiology in Human Subjects. Study funded by the National Institute of Justice, U.S. Department of Justice, 10/1/2005 to 9/30/2007. UCSD No. 2006-0846; USDOJ Federal Award #98-IJ-CX-0079. Amount: $213,941.49
  • Sloane, C. Evaluation of the Ventilatory and Respiratory Effects of a Restraint Chair on Human Subjects. Funded by the Institute for the Prevention of In-Custody Deaths, Inc, 1/1/07 to 12/31/07. Amount: $11,658.00
  • Co-Investigator (PI) for study entitled, “Ventilatory Effects of Prone Restraint on Obese Human Subjects.” Funded by the Institute for the Prevention of In-Custody Deaths, Inc, 1/1/09 to 12/31/09. Amount: $13,423
  • Co-Investigator (PI) for study entitled, “EXCITATION Study: Unexplained In-Custody Deaths: Evaluating Biomarkers of Stress and Agitation.” Study funded by the National Institute of Justice, U.S. Department of Justice, 11/1/2012 to 6/30/2016. USDOJ Federal Award # 2012-R2-CX-K006. Amount: $431,943

Brian K. Snyder, MD

  • Snyder, B. “ IMPAACT – Translating Research into Practice Study (study examining antibiotic prescribing, patient education and the use of C-reactive protein in upper respiratory infections)”. AHRQ. 2003 - 2007. (Amount - $ 60,000).
  • Snyder, B. “National Emergency Department Safety Study (study examining Emergency department patient safety issues through staff surveys and chart reviews)”. AHRQ. 2004 - 2006. (Amount - $3,600).
  • Snyder, B.Site Principal Investigator for the Multicenter Airway Research Collaboration. MARC undertakes a variety of studies examining asthma and COPD involving over 400 Emergency Departments worldwide. July 2000 to present. Participated in :
    • MARC-5.4a Adult ED patients with acute asthma 2003 ($1000)
    • MARC-14 Examining resistance patterns in S. pneumoniae bacteremia 2002-3 ($2000)
    • MARC 29 Examining ACE inhibitor Angioedema 2007 ($5000)
    • MACR 36 Adult ED patients with acute asthma and survey of local asthma centers 2013 ($3500)
  • Site Principal Investigator for the IMPAACT – Translating Research into Practice Study. An AHRQ funded, multiyear, multicenter study examining antibiotic prescribing, patient education and the use of C-reactive protein in upper respiratory infections. November 2003 to July 2007. ($60,000)
  • Site Principal Investigator for the National Emergency Department Safety Study. An AHRQ funded multicenter study examining Emergency department patient safety issues through staff surveys and chart reviews. September 2004 to March 2006. ($3800)

Radhika Sundararajan, MD, PhD

  • Principal Investigator. "Use of Traditional Healers by Patients at Risk of HIV Infection in Mozambique: A Qualitative Study." Funded by UCSD Health Sciences Academic Senate. Amount: $10,000
  • Principal Investigator. "Characterizing the knowledge, attitudes, and current practices of Mozambican Traditional Healers for patients in an HIV-endemic area." Funded by UCSD Center for AIDS Research. Amount: $38,500

Christian A. Tomaszewski, MD

  • Co-Principal Investigator with Dr. Edward M. Castillo, for study entitled, "Mitigating Legal Risk in the Emergency Department: A UC Health System Wide Collaboration" funded by University of California Office of the President, Division of Health Sciences and Services, Center for Health Quality and Innovation. Amount: $264,465

Gary M. Vilke, MD

  • Co-Investigator with Tom Neuman (PI) for evaluation of positional asphyxia in the hobble restraint position, funded by the County of San Diego, 1995--$33,900
  • Co-Investigator, with Theodore Chan (PI), for evaluation of the Melker percutaneous cricothyrotomy kit in human cadavers, funded by Cook Medical Products, 1997--$10,000 Co-Investigator with John Eisele (PI) for the evaluation of positional asphyxia in the hobble restraint position with weight on subjects' backs, funded by the American Academy of Forensic Sciences, 1998--$2,500
  • Co-Investigator, with Theodore Chan (PI), for study entitled, “The Impact of Oleoresin Capsicum Spray on Respiratory Function in Human Subjects in the Sitting and Prone Maximal Restraint Positions.” Study funded by the National Institute of Justice, U.S. Department of Justice, 1998-99. UCSD No. 98-7107; USDOJ Federal Award #98-IJ-CX-0079. Amount: $128,176
  • Principle Investigator (PI) for study entitled “Evaluation of Hurricaine anesthetic in patients with dyspepsia” funded by Beutlich Pharmaceuticals for, 2001. Amount: $1,500
  • Co-Investigator, with Theodore Chan (PI), for evaluation of the Melker percutaneous cricothyrotomy kit in human cadavers, funded by Cook Medical Products, 2003. Amount: $12,000
  • Co-Investigator, with David Hoyt (PI) for the Resuscitation Outcomes Consortium: UCSD / San Diego Resuscitation Research Center, funded by the NIH, 9/1/04 to 6/30/09. UO1 HL077908. Amount: $2,250,522
  • Co-Principal Investigator (Co-PI), with Theodore Chan, for study entitled, “The effect of Taser on Cardiac, Respiratory and Metabolic Physiology in Human Subjects.” Study funded by the National Institute of Justice, U.S. Department of Justice, 10/1/2005 to 9/30/2007. UCSD No. 2006-0846; USDOJ Federal Award #98-IJ-CX-0079. Amount: $213,941.4
  • Co-Investigator, with Daniel Davis (PI) for the study entitled, “ROC Interventional Trials: Hypertonic Resuscitation for Traumatic Injury, Trauma Epistry, PRIMED”, funded by the NIH, 7/1/06 to 6/30/08. UO1 HL077863. Amount: $331,320
  • Co-Investigator, with Daniel Davis (PI) for the, “ROC Cardiac Epistry”, funded by the AHA, 7/1/06 to 6/30/08. Amount: $133,427
  • Co-Investigator, with Theodore Chan (PI) for study entitled, “Multi-Center Study of the Impact of Nurse-Patient Ratios on Emergency Department Overcrowding.” funded by the Emergency Medicine Foundation, 7/1/07 to 6/30/08. Amount: $50,000
  • Principal Investigator (PI) for study entitled, “Evaluation of the Ventilatory and Respiratory Effects of a Restraint Chair on Human Subjects.” Funded by the Institute for the Prevention of In-Custody Deaths, Inc, 1/1/07 to 12/31/07. Amount: $11,658
  • Co-Investigator, with Edward Castillo (PI) for study entitled, “California ED Diversion Project Evaluation.” funded by the California Healthcare Foundation, 5/15/08 to 10/15/08. Amount: $50,990
  • Principal Investigator (PI) for study entitled, “Ventilatory Effects of Prone Restraint on Obese Human Subjects.” Funded by the Institute for the Prevention of In-Custody Deaths, Inc, 1/1/09 to 12/31/09. Amount: $13,423
  • Principal Investigator (PI) for study entitled, “FAST TRAC: Finding ACS with Serial Troponin Testing for Rapid Assessment.” Funded by the Nanosphere, Inc. 2/1/09 to 2/1/11. Amount: $85,000
  • Principal Investigator (PI) for study entitled, “CHOPIN: Copentin Helps in the Early Detection of Patients with Acute Myocardial Infarction.” Funded by Brahms AG, 8/1/09 to 8/1/12. Amount: $103,950
  • Co-Investigator, with Christine Hall for the study titled, “RESTRAINT - Risk of dEath in Subjects That Resisted: Assessment of Incidence and Nature of faTal events”, funded by the Vancouver Island Health Authority. 7/1/09 to 6/30/11. Amount $50,000
  • Co-Investigator for study titled “STAT MERCURY: Studying the Treatment of Acute HyperTension: A Multicenter EmeRgency Department Clevidipine Utilization RestrY” funded by the Medicines Company, 7/27/10 to 11/1/11. Amount $1400
  • Co-Investigator for study titled “A Phase II, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of MN-221 when Administered Intravenously as an Adjunct to Standard Therapy to Adults with an Acute Exacerbation of Asthma.” Study funded by MediciNova, Inc. 1/1/11 to 1/31/12. Amount $50,000
  • Principle Investigator for study titled “AKINESIS: Acute Kidney Injury N-gal Evaluation of Symptomatic heart failure.” Study funded by Alere and Abbott, 4/1/11 to 6/30/12. Amount $32,000
  • Principle Investigator for study titled “Evaluation of Ecallantide (DX-88) for the Acute Treatment of Angiotensin Converting Enzyme Inhibitor Induced Angioedema, a Phase II, double-blind study. Study funded by Dyax Corporation. 4/1/11 to 6/30/12. Amount $20,000
  • Principle Investigator for study titled “REAL: Rapid Evaluation of Acute Kidney Injury with NGAL in Acutely Ill Patients in the ICU.” Study funded by Alere, 5/1/11 to 6/30/12. Amount $74,435
  • Principle Investigator for study titled “A Mulit-Center, Open-Label, Surveillance Trial to Evaluate the Safety and Efficacy of a Shortened Infusion Time of Intravenous Ibuprofen Protocol CPI-CL-015.” Study funded by Cumberland Pharmaceuticals, Inc., 6/1/11 to 6/30/12. Amount $50,000
  • Principal Investigator (PI) for the study titled, “Resuscitation Outcomes Consortium (ROC) Regional Clinical Center, San Diego”, funded by the NIH, 7/1/14 to 12/31/15. U01 HL077908-09. Amount: $1,389,389
  • Principal Investigator (PI) for study entitled, “EXCITATION Study: Unexplained In-Custody Deaths: Evaluating Biomarkers of Stress and Agitation.” Study funded by the National Institute of Justice, U.S. Department of Justice, 11/1/2012 to 6/30/2016. USDOJ Federal Award # 2012-R2-CX-K006. Amount: $431,943
  • Principal Investigator (PI) for the study titled, “Resuscitation Outcomes Consortium (ROC) Protocol -ALPS”, funded by the NIH, 7/1/13 to 12/31/15. 5U01HL077863-11 subaward 758500. Amount: $289,003
  • Co-Investigator with Edward Castillo (PI) for study entitled, “Acute Home Care as an Alternative to Inpatient Admission from the Emergency Department”. Funded by the Gary and Mary West Health Institute, 2015 – 20/16. Amount: $499,125.
  • Co-Investigator with Theodore Chan (PI) for study entitled, “The Gary and Mary West Geriatric Center of Excellence (West COE): Phase 1 Research Development”. Funded by the Gary and Mary West Health Institute, 2015-2016. Amount: $243,610.
  • Co-Investigator, with Edward Castillo (PI) for the study titled, “Restraint Chair Literature Review and Policy Gap Analysis", funded by the Ontario Ministry of Community Safety and Correctional Services, 7/1/13 to 9/30/13. COS-0010. Amount: $15,000
  • Co-Investigator, with Daniel Davis (PI) for the study titled, “Resuscitation Outcomes Consortium (ROC) Regional Clinical Center, San Diego”, funded by the NIH, 3/1/10 to 6/30/14. U01 HL077908-09. Amount: $1,389,389
  • Co-Investigator with Edward Castillo (PI) for study entitled, “Diagnostic Evaluation using ClearView in Decision Making in the Emergency Room”. Funded by EPIC Research and Diagnostics, Inc, 2012-2014. Amount: $650,840.10 (based on 570 total participants).
  • Co-Investigator with Edward Castillo (PI) for study entitled, “Point-of-Care Testing for Illicit Drugs and Alcohol Intoxication in an Emergency Room”. Funded by the National Institute on Drug Abuse through Seacoast Science, Inc., 2013-2015. Amount: $50,163.
  • Co-Investigator with Edward Castillo (PI) for study entitled, “Evaluation of downward force placed onto prone subjects.” Funded by the Institute for the Prevention of In-Custody Deaths, Inc., 2014-2015. Awarded, contract in process. Amount: $7,500.
  • Co-Investigator with Edward Castillo (PI) for study entitled, “Acute Bacterial Skin and Skin Structure Infection (abSSSI) Practice Pattern Assessment.” Funded by Durata Therapeutics International B.V., 2014-2015. Amount: $15,000.
  • Co-Investigator with Edward Castillo (PI) for study entitled, “Exploring emergency room physician’s knowledge and attitudes concerning the use of appropriate and safe home care as an alternative to hospital admission.” Funded by the Gary and Mary West Health Institute, 2014-2015. Amount: $118,021.