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Loren K. Mell, MD

Loren K. Mell, MD

Associate Professor

Head and Neck Malignancies
Gynecologic Malignancies

Contact Information

Dr. Mell graduated from Stanford University in 1996, where he received degrees in Mathematics (BS) and Economics (BA). He received his MD from the University of Chicago in 2003. After completing his internship, he returned to the University of Chicago for residency, where he was named Chief Resident. He has expertise in medical statistics and clinical trial design and has previously worked for the National Bureau of Economic Research in Palo Alto, California (1995-1997), and the Center for Health Studies in Seattle, Washington (1997-1999).

Dr. Mell serves as Chief of the Head and Neck Radiation Oncology Service and is the Director of the Clinical and Translational Research Division for the Department of Radiation Medicine and Applied Sciences. He also serves as Associate Director of the Center for Advanced Radiotherapy Technologies, which focuses on the innovation and clinical applications of novel radiation and related biotechnologies. His primary research interests include image-guided radiation therapy (IGRT), intensity modulated radiation therapy (IMRT), and clinical trial design. He is the Principal Investigator of multiple clinical trials at UCSD, including cooperative group studies conducted by the Radiation Therapy Oncology Group (RTOG), and oversees several nationally and industry-funded research grants.

He is the Principal Investigator of the International Evaluation of Radiotherapy Technology Effectiveness in Cervical Cancer (INTERTECC) Trial, an international Phase II/III trial of IMRT for patients with cervical cancer. His research explores the effectiveness of image-guided bone marrow sparing radiation techniques. He also is conducting Phase I clinical trials of gemcitabine for advanced cervical cancer and a novel oncolytic virus (GLONC1) for treatment of advanced head/neck cancer. Dr. Mell serves on several national committees including the Gynecologic Oncology Group (GOG) Cervix Committee, and the RTOG Gynecologic Cancer Working Group. He is an Associate Editor for the International Journal of Radiation Oncology Biology Physics, the leading journal in the field of radiation oncology. Outside work, Dr. Mell is a proud father of two sons, Ryan (10) and Elliot (6). He and his wife, Gina, a fitness instructor, were married in Seattle in 1999. He enjoys basketball, running, and hiking.