News and Events
Chemotherapy can be very effective against small prostate tumors. Larger prostate tumors, however, accumulate cells that suppress the body’s immune response, allowing the cancer to grow despite treatment. Researchers at the University of California, San Diego School of Medicine now find that blocking or removing these immune-suppressing cells allows a special type of chemotherapy — and the immune cells it activates — to destroy prostate tumors. This novel combination therapy, termed chemoimmunotherapy, achieved near complete remission in mouse models of advanced prostate cancer in a recent study published in Nature
. Urology faculty Christina Jamieson, PhD
, and Christopher J. Kane, MD,
collaborated on this study with Michael Karin, PhD, and his team in the Department of Pharmacology and researchers in Berlin and Vienna. UCSD Press Release
| UK Daily Mail
The 3rd Annual Breakfast with Champions was held Wednesday, September 30 at the La Jolla Country Club to raise funds for prostate cancer research, and featured 9-time NFL Pro Bowl safety and Fox sportscaster John Lynch. Also, Christopher J. Kane, MD talked about plans for the future of prostate cancer research and treatment at UC San Diego Health. More information
We are ranked at #25 and among the best in the nation for the fourth consecutive year according to the 2015-16 edition of US News & World Report
. Once again UC San Diego Health was named the #1 hospital in the San Diego metropolitan area and #5 in California. Urology is one of 12 specialties at UC San Diego Health in the top 50. Read more: UC San Diego Health Newsroom
Learn how eating too many leafy greens - such as spinach, rhubarb and beets - could lead to kidney stone formation. As noted in this article, another possible sign of a stone is a recurrent urinary tract infection - "not all stones cause pain, some can pass through your body unnoticed. But other times, kidney stones stay in your urinary tract and block the flow of urine, which could lead to a UTI. This infection is one possible sign that you may have a kidney stone that you don’t know about, explains Dr. Roger Sur of the UC San Diego Comprehensive Kidney Stone Center. 'In some people, the only way we would have found their kidney stones is because they had recurrent urinary tract infections." Read more about treatment and prevention and other risk factors: Time
A combination of heparin and alkalinized lidocaine provides significantly better relief of interstitial cystitis (IC) symptoms compared with alkalinized lidocaine alone, according to a new study led by C. Lowell Parsons, MD, of the Department of Urology at UC San Diego Health System, published recently in the Canadian Journal of Urology and featured in Renal & Urology News.
2015 Awards for Outstanding Faculty, Residents and Staff
Congratulations to our Urology faculty, residents and staff who received the following awards at our graduation ceremony in June: Ithaar H. Derweesh, MD, is the 2014-15 Urology Outstanding Faculty Educator; Jason Woo, MD, earned the AUA Lawrence F. Greene Award; and Omer Raheem, MD, received the George W. Kaplan Outstanding Research Resident Award (with Honorable Mentions to Hossein Mirheydar, MD, and Nishant Patel, MD). The award for Outstanding Physician Consultant was presented to David Karow, MD, PhD, Assistant Professor in the Department of Radiology. In addition, Eileen Silva, senior editor, received the 2015 Outstanding Urology Administrative Staff award and Kimberly Broms, RN, Assistant Director of Perioperative Services at Thornton Hospital, received the 2015 Outstanding Urology Nurse award.
Join us at 6:00 p.m. on Tuesday May 5, 2015 for a free seminar for men and women, featuring expert guidance from Mike Hsieh, MD,, Antoni Duleba, MD, and Sanjay Agarwal, MD, at UC San Diego Moores Cancer Center. More information and Registration
Recent Developments in Kidney Cancer/Surgery April 22 - San Diego Urological Society
Ithaar Derweesh, MD, will present the lecture at the April 22, 2015 meeting of the San Diego Urological Society, taking place at the San Diego Yacht Club. RSVP by April 17 to Info@SDurological.org. We hope to see you there! Flyer
By age 60, more than 50 percent of men in the United States suffer from benign prostatic hyperplasia (BPH), a condition that leads to annoying changes in urinary flow. While medical therapy is usually the first line of treatment, a new minimally invasive implant can dramatically reduce symptoms for men.“This is a safe procedure for men with BPH to improve urination while preserving sexual function,” said Mike Hsieh, MD, urologist at UC San Diego Health System. “This endoscopic procedure is done on an outpatient basis under light sedation with virtually no side effects.” The device, called UroLift, was FDA approved in 2013. UC San Diego Health System show-cased this new procedure in a live-surgery during the 8th annual UC San Diego School of Medicine urology postgraduate course in March 2015. See also Health Canal Uro Today
J. Kellogg Parsons, MD, MHS is the national PI on an innovative clinical trial funded by the National Cancer Institute and administered through the University of Arizona Early Phase Chemoprevention Consortium. Christina Jamieson, PhD, is the lead translational investigator. Prostate cancer is an attractive target for immunotherapy because it is a relatively slow-growing tumor, allowing time to elicit an effective immune response. In addition, prostate cells express many tissue-specific proteins that could act as therapeutic targets. This trial, entitled Phase II Randomized, Placebo-Controlled Trial of PROSTVAC (PSA-TRICOM) in Patients with Clinically Localized Prostate Cancer Undergoing Active Surveillance, is not yet open for enrollment.
UC San Diego’s Male Fertility and Sexual Health Program is the region’s only medical center with a specific focus on male fertility issues. Learn more about age-related hormonal changes, how erectile dysfunction (ED), is an early marker for cardiovascular disease, and other issues affecting men's sexual health from program director Mike Hsieh, MD.
UC San Diego Urology faculty are the first in San Diego to meld magnetic resonance imaging (MRI) technology with a traditional ultrasound prostate exam to create a three-dimensional map of the prostate that allows physicians to view growths that were previously undetectable. "An ultrasound machine provides an imperfect view of the prostate, resulting in an under-diagnosis of cancer," said Dr. J. Kellogg Parsons a urologic oncologist who, along with Dr. Christopher Kane and Dr. Karim Kader, is pioneering the new technology at UCSD Moores Cancer Center. See also: Science Blog UCSD Health System Newsroom Radiological Society of North America
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Christina Jamieson, PhD, is the UC San Diego Site PI on a small business innovation research grant with local biopharmaceutical company Targazyme, Inc. to develop genetically modified mesenchymal stem cells treated with Targazyme's lead product, TZ101, for treatment of oral mucositis. "Replenishing the mucous membrane tissues of the mouth and nose will relieve one of the most painful and serious side-effects of cancer therapies. Strengthening this tissue with TZ101 treated mesenchymal stem cells may also help patients fight off infections and help them to tolerate even more effective anti-cancer therapies," said Jamieson, Assistant Professor of Surgery. "We are grateful for this research support. I look forward to continuing our successful collaboration in hopes that we may bring treatments like this to patients with cancer more quickly."
Jill Buckley, MD, is featured in a recent article in Urology Times. In a retrospective study, surgeons from the Lahey Clinic in Burlington, MA, in collaboration with Buckley reported that a novel approach using radial urethrotomy with mitomycin C (MMC) injections led to a patent bladder neck in nearly three-fourths of patients after a single procedure and 81% after two procedures.
Once again UCSD Urology has 3 doctors on the San Diego Magazine Physicians of Exceptional Excellence list: Michael Albo, MD (10th year), J. Kellogg Parsons, MD, MHS (5th year) and Christopher Kane, MD (6th year). Overall, UC San Diego Health System has 110 physicians in 40 specialties on the 2014 list. These “Top Doctors” were rated among the best in San Diego County by their peers, members of the San Diego County Medical Society.
UCSD Urology received its highest ranking ever in the 2014-15 edition of US News & World Report. "This is a great statement about our collective progress in building a distinguished and outstanding Urology Department," says Christopher J. Kane, MD, Chair. Moving up from #22 last year, this is the fifth time the program has been in the top 50 nationally in the last seven years. In addition, UC San Diego Health System is again ranked #1 in the San Diego metropolitan area and #5 in California, with national rankings in 11 specialites, up from 10 last year. Read more: San Diego Union-Tribune
Dr. Kane and his team Kane's Crusaders rode the full 150 miles from UCSD to Temecula and back, and more than 750 cyclists participated in the annual Pedal the Cause event held September 20-21, 2014. All funds benefit cancer research in San Diego, including UC San Diego Moores Cancer Center. Sign up now to ride in 2015!
Christopher J. Kane, MD, was recently invited to join the American Association of Genitourinary Surgeons. AAGUS is composed of leading academic urologists and recognizes outstanding scholarly achievement in the field. It is one of the highest accolades a urologist in the U.S. may receive.
2014 Awards for Outstanding Faculty, Residents and Staff
Congratulations to our faculty and residents who received the following awards at the Urology graduation ceremony in June: T. Mike Hsieh, MD, is the 2013-14 Urology Outstanding Faculty Educator; Nishant Patel, MD, earned the AUA Lawrence F. Greene Award; and Jason Woo, MD, received the George Kaplan Resident Research Award (with Honorable Mentions to Seth A. Cohen, MD, and Hossein Mirheydar, MD). Our inaugural award for Outstanding Physician Consultant was presented to Dr. Alan Hemming, Chief of Abdominal Transplantation and Hepatobiliary Surgery. In addition, Ivanka Kodzic, administrative assistant in the Hillcrest Urology clinic, received the 2014 Outstanding Urology Administrative Staff award and Rowena Heck, RN, a nurse at the San Diego VA Medical Center, received the 2014 Outstanding Urology Nurse award.
The monthly Prostate Cancer Support Group meetings are temporarily on hiatus. Thank you for your patience.
Join us at 6:00 p.m. on Thursday, March 27, 2014 for a free seminar for men and women, featuring expert guidance from Mike Hsieh, MD, and Sanjay Agarwal, MD, at UC San Diego Moores Cancer Center. More information and Registration
Raw, bitter veggies could help slow prostate cancer, even in advanced stages
J. Kellogg Parsons, MD, presented findings from the MEAL Study at the Urological Society of Australia and New Zealand Annual Scientific Meeting in Brisbane in March. Sky News Australia
The 2nd Annual Breakfast with Champions was held on March 21 at the La Jolla Country Club to raise funds for prostate cancer research. Pro Football Hall of Famers Mike Haynes and Charlie Joiner shared their stories, and Christopher J. Kane, MD discussed innovations and discoveries in prostate cancer here in San Diego. More information
The 7th Annual UCSD Urology Postgraduate Course, Evidence-Based Urology Update was held March 14-15, 2014 at the Hyatt Regency Mission Bay in San Diego, with our highest number of attendees and exhibitors to date. We recevied very positive feedback on the content and live surgery. Thank you to all who attended, and we look forward to seeing you in 2015!
UCSD Urology received its highest ranking ever in the 2013-14 edition of US News & World Report. "This is a great statement about our collective progress in building a distinguished and outstanding Urology Department," says Christopher J. Kane, MD, Chair. This is the fourth time the program was in the top 50 nationally in the last six years. In addition, UC San Diego Health System is ranked #1 in San Diego and among the best in the nation. Read more
Movember Spotlights Men's Health
Christopher J. Kane, MD, was interviewed by KPBS for the annual "Movember" event, which encourages men to grow a mustache for the month of November to raise awareness for prostate and testicular cancer and mental illness. Video and audio interviews
Moores Cancer Center Team Raises Funds with Pedal the Cause
Urology Department Chair Christopher J. Kane, MD and UC San Diego Health System CEO Paul Viviano were among the more than 400 cyclists who used pedal power to raise money for cancer research at the inaugural Pedal the Cause – San Diego held Oct. 25 and 26. Proceeds from the event benefit research at UC San Diego Moores Cancer Center, Sanford-Burnham Medical Research Institute and the Salk Institute for Biological Studies. Read more
MAN UP! Take Charge of Your Health - October 5, 2013
Drs. Mike Hsieh and Christopher Kane gave talks on men's sexual health after 40 and PSA screenings, respectively, at the free MAN UP! event held on the UC San Diego School of Medicine campus in La Jolla, Calif. The event, sponsored by the Mighty 1090AM radio station, also included talks on cardiovascular health, exercise, a male survival guide to stress, and a Q&A session. Read more
New Study on Kidney Sparing Surgery
Recent findings published by Ithaar Derweesh, MD, and colleagues show that patients most in need of kidney-sparing surgery are still more likely to undergo a total nephrectomy. Read more Abstract
Updated AUA Guidelines for Prostate Cancer Screening
The American Urological Association released updated guidelines for prostate cancer screening at its annual meeting in San Diego, recommending that men ages 55 through 69 with an average risk of developing prostate cancer receive prostate-specific antigen, or PSA, blood tests every two years. However, men with an increased risk of developing the disease, such as those who have had a close family member (father, uncles, brothers or cousins) diagnosed with prostate cancer and men of African-American ethnicity, are recommended to begin the screening process earlier, at age 45. Men in these two groups are also more likely to develop more aggressive forms of prostate cancer, according to J. Kellogg Parsons, MD. Read more
Ureteroscopy Use Rising, SWL Use Falling in California
The research of Hossein S. Mirheydar, MD, Roger L. Sur, MD, and colleagues was presented at the American Urological Association's annual meeting in San Diego and featured in Renal & Urology News. Ureteroscopy use has increased and shock wave lithotripsy use has decreased in California such that the two treatments for kidney stones are now being used at nearly equal rates. Read more and watch video
Demystifying Myths About Fertility - Free Seminar March 27
Join us at 6:00 p.m. on Wednesday March 27, 2013 for a free seminar by Mike Hsieh, MD, and Sanjay Agarwal, MD, at the Moores Cancer Center. More information and Registration Listen to Radio Ad
Watch interviews with Mike Haynes and Christopher Kane, MD, from the recent fundraiser at La Jolla Country Club.
- NFL Hall of Famer and prostate cancer survivor Mike Haynes participated in a fundraiser at the La Jolla Country Club on Friday, Feb. 22, 2013. Dr. Christopher Kane, Division Chief for Urology, gave an update on new detection methods for prostate cancer, and shared some of the exciting prostate cancer research taking place at UC San Diego.
US News and World Report ranked the Division of Urology No. 37, the highest ranking in the division's history and the third time that the division has been in the top 50 nationally in the last five years.
All faculty and residents are encouraged to attend the first Surgery Research Showcase and share your research with your colleagues.
The public is invited to learn about robotic surgeries at Moores Cancer Center and test-drive a da Vinci Surgical System as part of Cancer Survivor Week. Dr. Kader will present new robotic treatments for bladder cancer.
All San Diego Urologists, UCSD Alumni and Friends are invited to the Annual AUA Reception on May 21 at the Omni Hotel in Atlanta. See above link for details.
Dr. Kane asked for comment on Warren Buffett
Financier Warren Buffett was recently diagnosed with Stage 1 prostate cancer. MSNBC.com asks Division of Urology Chief Dr. Christopher Kane for his opinion on the prognosis. Read more
NIH Study Shows Increased Prostate Cancer Risk from Vitamin E Supplements
An updated review of data from the Selenium and Vitamin E Cancer Prevention (SELECT) Trial was recently published in the Journal of the American Medical Association. According to J. Kellogg Parsons, MD, MHS, one of the authors, “SELECT has definitively shown a lack of benefit from vitamin E and selenium supplements in the prevention of prostate cancer, and has shown there are some real risks.” Read more
Kidney-Preserving Surgery and Reduced Risk of Osteoporosis
New research from UCSD and the University of Tennessee shows that, compared to radical nephrectomy, partial nephrectomy is associated with less risk of osteoporosis later in life. "When weighing the risks and benefits of partial versus radical nephrectomy, doctors and patients should take into account the impact on a patient's bone health," says Ithaar Derweesh, MD, Associate Professor at UCSD and senior author of the paper, published in Urology.
Dr. Kane Appointed C. Lowell & JoEllen Parsons Endowed Chair
In May 2011, internationally recognized cancer surgeon Dr. Christopher J. Kane became the inaugural holder of the C. Lowell and JoEllen Parsons Endowed Chair in Urology. The $2.5 million endowed faculty chair will enable Dr. Kane to recruit world-class talent and support novel research, cancer treatment and prevention programs at UC San Diego Health System. Read more
Diet and Prostate Cancer Trial
UC San Diego is launching the nation's first non-supplement study on prostate cancer and diet. Participants in the Men's Eating and Living (MEAL) study will eat at least seven servings of colorful, strong-flavored produce per day, with an emphasis on cruciferous vegetables and tomato products, as well as whole grains, beans or other legumes, and fruit. "Ours is the first study to focus on changing the entire lifestyle rather than just giving the participants a supplement pill," says Dr. J. Kellogg Parsons,urologic oncologist at the UCSD Moores Cancer Center. Read more about the MEAL study or watch the 10News video coverage.
San Diego's Top Doctors 2011
Michael Albo, MD, J. Kellogg Parsons, MD, and Christopher Kane, MD were named among San Diego's Top Doctors by the San Diego County Medical Society, in partnership with San Diego Magazine. This is the eighth consecutive year Albo has received this recognition, the second consecutive year for Parsons, and the third consecutive year for Kane.
Health Care Champion
The San Diego Business Journal recognized Christopher J. Kane, MD, as Health Care Champion-Physician for 2010.
Reviewers of the Year
The June 2010 issue of the Journal of Urology recognizes Dr. C. Lowell Parsons as Best Reviewer of the Year in the field of urodynamics/incontinence/female urology, and Dr. J. Kellogg Parsons as Outstanding Reviewer of the Year in the field of benign prostatic hyperplasia. (Article access restricted to UC campuses.)
Novel Treatment Shrinks and Removes Large Tumors, Saves Kidneys
A team of UCSD researchers led by Dr. Ithaar Derweesh has successfully used sunitinib to shrink large kidney tumors in patients at high risk for kidney failure. They then surgically removed the tumors and reconstructed the kidneys. Patients did not require dialysis after surgery. The study was published in the April 2010 issue of BJU International. Read more.
Risk of Stones After Radical vs Partial Nephrectomy
A new study by Ithaar Derweesh, MD, and colleagues found that patients undergoing partial nephrectomy have a significantly decreased incidence of postoperative nephrolithiasis compared to those undergoing radical nephrectomy. This is the largest single-institution study ever conducted to evaluate the association of radical versus partial nephrectomy with subsequent stone formation. Read more in BJU International.
Prostate Cancer Treated Differently at County vs Private Hospitals
A study headed by UC San Diego's J. Kellogg Parsons, MD found that treatment decisions among economically disadvantaged men with prostate cancer are related to the type of facility where they are treated.
Parsons and colleagues at UCLA compared the types of treatments received by 559 men enrolled in a state-funded program for low-income patients, Improving Access, Counseling and Treatment for Californians with Prostate Cancer (IMPACT). Those who were treated at private hospitals were found to be two and half times more likely than those at county hospitals to receive radiation therapy and four and a half times more likely to initially receive hormone therapy instead of surgery.
While the reasons for these differences in treatment decisions are not known, the type of doctor that patients see may play a role. At county hospitals, patients were initially under the care of urologists, while the initial providers at private facilities were urologists, radiation oncologists, and medical oncologists.
These differences have "implications for health policy, quality of care, and equality of care—particularly because public hospitals are funded by city and state governments to provide health care for underserved, poor populations,” said Parsons.
The study was published in the March 2010 issue of the journal Cancer.
Single-Incision Tumor Removal and Kidney Reconstruction
A team of surgeons led by Dr. Ithaar Derweesh performed a complex, single-incision surgery to remove a kidney tumor while preserving and then reconstructing the remaining healthy kidney. The UCSD team is the second in the world to perform this procedure. Read more.
Medical News Base
Medical News Today
See also: KPBS
New Drug Provides Hope for Sufferers of Interstitial Cystitis/Painful Bladder Syndrome
A new patent has been issued for an experimental drug therapy developed by Dr. C. Lowell Parsons. The drug therapy, which has yielded positive results in a recent Phase 2 study, is a combination of an anesthetic and heparin delivered directly into the bladder via a catheter. The anesthetic provides rapid pain relief while heparin restores the protective mucus layer of the bladder. Read more.
New York Times
Medical News Today
America’s Best Children's Hospitals
The 2010 childrens hospital rankings from U.S. News & World Report rank Rady Children's Hospital-San Diego number 12 in the country for pediatric urologic care.