LRF MoMI CoRE Director Dr. Lars Bode is leading a new project to identify and synthesize human milk oligosaccharides (HMOs) to prevent environmental enteric dysfunction (EED) and diarrheal disease. EED and diarrheal disease have far-reaching impacts on child growth, health, and development in low- and middle-income country settings. Diarrhea remains to be one of the major causes of death in children under the age of 5.
The two-year project is funded with over $1.7M in support from the Bill & Melinda Gates Foundation and uses a collaborative, multi-dimensional approach to assess in vitro and
in vivo efficacy of HMOs and identify specific HMO structures responsible for the beneficial effects.