Dr. David Karow's RSI interview with KUSI News at 6-00PM

Genetics Overlap Found Between Alzheimer’s Disease and Cardiovascular Risk Factors

Inflammation and high blood lipids may play role in dementia risk, but also offer therapeutic targets
UCSD Press Release – April 16, 2015

An international team of scientists, led by researchers at University of California, San Diego School of Medicine, have found genetic overlap between Alzheimer’s disease (AD) and two significant cardiovascular disease risk factors: high levels of inflammatory C-reactive protein (CRP) and plasma lipids or fats. The findings, based upon genome-wide association studies involving hundreds of thousands of individuals, suggest the two cardiovascular phenotypes play a role in AD risk – and perhaps offer a new avenue for potentially delaying disease progression. The findings are published in current online issue of Circulation. …

CTIPM Director Dr. Anders Dale was a senior author of this study.
Dr. James Brewer, co-director of Neurology & Neuro-Imaging at CTIPM, and Dr. David Karow, director of Oncologic Imaging at CTIPM, were co-authors of the study.

Family income, parental education related to brain structure in children and adolescents

Children’s Hospital Los Angeles – March 30, 2015

Characterizing associations between socioeconomic factors and children's brain development, a team including investigators from nine universities across the country reports correlative links between family income and brain structure. Relationships between the brain and family income were strongest in the lowest end of the economic range - suggesting that interventional policies aimed at these children may have the largest societal impact. The study, led by researchers at The Saban Research Institute of Children's Hospital Los Angeles and Columbia University Medical Center, will be published in the early online edition of the journal Nature Neuroscience on March 30. …

Contributors to this study included CTIPM Director Dr. Anders Dale, Informatics Director Hauke Bartsch, and Imaging Technology Co-Director Joshua M. Kuperman.

Neuroimaging Advances for Alzheimer's Disease - On Our Mind

The Brain Channel, UCSD TV – Feb. 16, 2015

What insights into Alzheimer's disease can cutting edge imaging techniques reveal? James Brewer, MD, PhD joins William Mobley, MD, PhD to discuss how this unique window into the brain can be used to study the progression of the disease as well as help test new therapies.

Dr. James Brewer is co-director of Neurology & Neuro-Imaging at CTIPM

Novel Imaging Technique Improves Prostate Cancer Detection

More accurate diagnoses could mean less invasive interventions, more surveillance
UCSD Press Release – January 6, 2015

In 2014, prostate cancer was the leading cause of newly diagnosed cancers in men and the second leading cause of cancer death in men. Writing in the January 6, 2015 issue of the journal Prostate Cancer and Prostatic Disease, a team of scientists and physicians from the University of California, San Diego School of Medicine, with counterparts at University of California, Los Angeles, describe a novel imaging technique that measurably improves upon current prostate imaging – and may have significant implications for how patients with prostate cancer are ultimately treated. …

Nathan White, co-director of Information Technology at CTIPM, was the study’s co-author and co-inventor of the RSI-MRI technique. Dr. David Karow, Director of Oncologic Imaging at CTIPM, was the study’s corresponding author. Other co-authors included CTIPM Director Dr. Anders Dale, Imaging Technology Co-Director Joshua M. Kuperman, and Informatics Director Hauke Bartsch.

Related News Coverage

Frontline Cancer: A ‘game-changer’ for prostate biopsies

La Jolla Light, Dec. 23, 2014

New Imaging Technique Improves Prostate Cancer Detection And Treatment

Prostate Cancer News Today, March 13, 2015

Scientists at UCSD and UCLA reveal new imaging system to fight prostate cancer

KUSI News, Jan. 6, 2015