Joseph Califano, MD
Professor of Surgery
Director, Head and Neck Cancer Center
As a world-class physician-scientist, Joseph Califano, MD, has translated multiple discoveries from his own laboratory into the clinic, including the application of sequencing technologies to create an early detection method for HPV-related and other head and neck cancers. Dr. Califano joined our faculty in 2015 as Professor of Surgery and Vice Chief of the Division of Otolaryngology-Head and Neck Surgery, Department of Surgery as well as Director, Head and Neck Cancer Center, Moores Cancer Center at UC San Diego Health. His major focus is the clinical practice of head and neck surgical oncology and the integration of basic, molecular biologic research in that practice. Dr. Califano brings his skills of integrating multiple specialty providers and coordinating areas of expertise needed to optimize care for these complex patients in an efficient and effective manner.
A graduate of Harvard Medical School, Dr. Califano performed his Otolaryngology-Head and Neck Surgery residency at Johns Hopkins Hospital, and completed a fellowship in head and neck surgical oncology at Memorial Sloan-Kettering Cancer Center. He then joined the faculty of Johns Hopkins and ultimately became Professor in the Head and Neck Division and the Division of Head and Neck Cancer Research at John Hopkins Department of Otolaryngology-Head and Neck Surgery and Department of Oncology at Johns Hopkins as well as the Medical Director of the Milton J. Dance Head and Neck Center at Greater Baltimore Medical Center.
His interests include minimally invasive treatment of tumors of the oral cavity, larynx, pharynx, thyroid, and neck, with an interest in tumors of the skull base, salivary glands, and premalignant conditions of the upper aerodigestive tract. He is actively participating in several areas of investigation including integrative network based molecular analysis of head and neck tumors, detection of recurrent and occult cancer within blood and saliva using molecular biologic techniques, and defining the underlying biology of head and neck cancers. He currently serves as principal investigator for clinical trials investigating the modulation of immune suppression in head and neck cancer with Cialis.
Dr. Califano is a clinically active head and neck surgeon and currently directs a laboratory focused on the molecular biologic basis of head and neck cancer. He has published over 230 peer reviewed articles related to both the clinical and basic scientific aspects of cancer, and serves on a variety of professional organizations and editorial boards.
Joseph Califano, MD