In Vivo Imaging

Director

David R. Vera, PhD
Professor of Radiology
E-mail: dvera@ucsd.edu

Consulting Services

David R. Vera, PhD
  • Radiopharmaceuticals and tracers
Carl Hoh, MD
  • PET and gamma camera imaging
David Hall, PhD, DABR
  • Optics, fluorescent and photoacoustic imaging
Jiang Du, PhD
  • MR imaging and contrast

Contact

Chris Barback
IVISR Manager                                                                                                                                                                    Phone: (858) 822-2862
Email: cbarback@ucsd.edu
Location: Moores Cancer Center, Room B211

Service profile

Equipment profile

  • MRSolutions 4000MRS MR
  • VisualSonics Vevo LAZR 2100
  • GE eXplore Vista PET
  • GE eXplore Locus CT
  • GE eXplore Optix
  • BioSpace Gamma Camera

Overview

The IVISR provides MR, photoacoustic, CT, ultrasound, high-resolution planar gamma imaging, and PET of mice and rats. Support and expertise includes imaging physics, biological applications, animal support, image computation, optical hardware and software, diagnostic agent chemistry, preparation of F18 labeled radiotracers, and kinetic modeling.

Up to 4.7T MR imaging allows for rapid acquisition of high resolution volumes both with and without contrast. Photoacoustic imaging can create high definition images of fluorescent optical markers at greater depths, overlaid across clear ultrasound images of anatomy. High-resolution optical imaging complements MR and PET imaging by increasing image quantitation and kinetic modeling. High- resolution ultrasound imaging permits quantitation of tumor size, as well as, measurement of left ventricular volume for recovery correction of MR and PET sampled input functions. Most importantly it permits the use of in situ tumor models. A key contribution of ultrasound to cancer research in mice is the ability to image in sterile fashion and to do so without the need for anesthesia. This permits frequent monitoring of tumor growth or regression following interventions.

Scheduling

Since all equipment requires training before independent use, scheduling is maintained by the IVISR manager. Please contact Christ Barback via email (cbarback@ucsd.edu) or phone (858 822-2862) to discuss booking time on the machines and hourly rates, as well as developing protocols or procedures.

Location

Most of the IVISR equipment is maintained in room B210 of the Moores Cancer Center, however the MRI is located next door in B207.