Research

Mandyam Lab

Chitra Mandyam, Ph.D.
Associate Professor
University of California San Diego (UCSD)

Research Biologist
Veterans Medical Research Foundation,
VA San Diego Healthcare System

3350 La Jolla Village Drive, Building 1, Room 6130E
San Diego, CA 92161
Office: 858.552.8585 ext. 7105
Email: cmandyam@ucsd.edu

Other Joint Appointments

Associate Adjunct Professor, Skaggs School of Pharmacy and Pharmaceutical Sciences, UCSD

Member, Graduate program in neurosciences, UCSD
Associate Professor Adjunct, The Scripps Research Institute, California Campus

Research Focus

Our research is funded by the National Institutes of Health, the Department of Veterans Affairs and start-up funds from Veterans Medical Research Foundation. The main research questions investigated in the laboratory include:

  1. Investigation of the functional significance of the process of neurogenesis (birth and generation of new neurons in the adult mammalian brain) in substance use disorder. 
  2. Investigation of the functional significance of the process of oligodendrogenesis (generation of oligodendrocytes that make myelin cells in the adult mammalian brain) in alcohol use disorder. 
  3. Investigation of the role of cholesterol-binding, membrane/lipid raft proteins in the brain in substance use disorder. These investigations are performed in preclinical models of addiction (specifically methamphetamine and alcohol addiction) with the belief that our findings will help determine and generate novel therapeutic strategies to reduce propensity for relapse and combat addiction to illicit drugs.

View our recent publications  


Mandyam Lab 2012: (We host high school students from the LSSI program and pharmacy graduate students from Skaggs School of Pharmacy, UCSD)


Mandyam Lab 2014: (L-R, Ivan Navarro, Sucharita Somkuwar, Chitra Mandyam, Phillip Silva, McKenzie Fannon, Melissa Galinato, Atoosa Ghofranian)


Melissa Galinato graduates from the department of Neurosciences, UCSD


Mandyam Lab 2017: (L-R, McKenzie Fannon, Chitra Mandyam, Noah Steiner, Karthik Mysore, Leon Quach, Sucharita Somkuwar, Michelle An)