Select and Recent Papers

Full List from PubMed

Regeneration of fat cells from myofibroblasts during wound healing
Plikus MV, Guerrero-Juarez CF, Ito M, Li YR, Dedhia PH, Zheng Y, Shao M, Gay DL, Ramos R, His TC, Oh JW, Wang X, Ramirez A, Konopelski SE, Elzein A, Wang A, Supapannachart RJ, Lee HL, Lim CH, Nace A, Guo A, Treffeisen E, Andl T, Ramirez RN, Murad R, Offermanns S, Metzger D, Chambon P, Widgerow AD, Tuan TL, Mortazavi A, Gupta RK, Hamilton BA, Millar SE, Seale P4,16, Pear WS, Lazar MA, Cotsarelis G (2017)
Science 355, 748-752.
​Identification of novel loci affecting circulating chromogranins and related peptides
Benyamin B, Maihofer AX, Schork AJ, Hamilton BA, Rao F, Schmid-Schönbein GW, Zhang K, Mahata M, Stridsberg M, Schork NJ, Biswas N, Hook VY, Wei Z, Montgomery GW, Martin NG, Nievergelt CM, Whitfield JB, O'Connor DT (2017). Human Molecular Genetics 26, 233-242.
Deleting an Nr4a1 Super-Enhancer Subdomain Ablates Ly6Clow Monocytes while Preserving Macrophage Gene Function
Thomas GD, Hanna RN, Vasudevan NT, Hamers AA, Romanoski CE, McArdle S, Ross KD, Blatchley A, Yoakum D, Hamilton BA, Mikulski Z, Jain MK, Glass CK, Hedrick CC. (2016)
Immunity 45, 975-987.
Deep Reads: Favorites from a few different shelves
Hamilton B. A. (2016)
PLoS Genetics 12, e1006476. [Open Access]
Zfp423 regulates Sonic hedgehog signaling via primary cilium function
Hong C.-J. and Hamilton B. A. (2016)
PLoS Genetics 12, e1006357. [Open Access]
bioRxiv preprint
Nmf9 encodes a highly conserved protein important to neurological function in mice and flies
Zhang S., Ross K. D., Seidner G. A., Gorman M. R., Poon T. H., Wang X., Keithley E. M., Lee, P. N., Martindale M. Q., Joiner W. J., and Hamilton B. A. (2015)
PLoS Genetics 11, e1005344. [Open Access]
Nxf1 Natural Variant E610G Is a Semi-dominant Suppressor of IAP-Induced RNA Processing Defects
Concepcion D., Ross K. D., Hutt K. R., Yeo G. W., and Hamilton B. A. (2015)
PLoS Genetics 11, e1005123. [Open Access]
Zfp423 binds autoregulatory sites in p19 cell culture model
Cho Y.-W., Hong C.-J., Hou A., Gent P. M., Zhang K., Won K.-J., and Hamilton B. A. (2013)
PLoS One
8, e66514. [Open Access]
Retrotransposon Activates Ectopic Ptf1a Expression: A Short Tail. (Perspective)
Hamilton B. A. (2013)
PLoS Genetics 9, e1003331. [Open Access]
Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling.
Chaki M, Airik R, Ghosh AK, Giles RH, Chen R, Slaats GG, Wang H, Hurd TW, Zhou W, Cluckey A, Gee HY, Ramaswami G, Hong CJ, Hamilton BA, Cervenka I, Ganji RS, Bryja V, Arts HH, van Reeuwijk J, Oud MM, Letteboer SJ, Roepman R, Husson H, Ibraghimov-Beskrovnaya O, Yasunaga T, Walz G, Eley L, Sayer JA, Schermer B, Liebau MC, Benzing T, Le Corre S, Drummond I, Janssen S, Allen SJ, Natarajan S, O'Toole JF, Attanasio M, Saunier S, Antignac C, Koenekoop RK, Ren H, Lopez I, Nayir A, Stoetzel C, Dollfus H, Massoudi R, Gleeson JG, Andreoli SP, Doherty DG, Lindstrad A, Golzio C, Katsanis N, Pape L, Abboud EB, Al-Rajhi AA, Lewis RA, Omran H, Lee EY, Wang S, Sekiguchi JM, Saunders R, Johnson CA, Garner E, Vanselow K, Andersen JS, Shlomai J, Nurnberg G, Nurnberg P, Levy S, Smogorzewska A, Otto EA, Hildebrandt F. (2012)
Cell 150, 533-548. [Free PMC]
Modifier Genes and the Plasticity of Genetic Networks in Mice.
Hamilton, B. A. and Yu, B. D. (2012)
PLoS Genetics
8, e1002644. [Open Access]
Modifier genes and non-genetic factors reshape anatomical deficits in Zfp423-deficient mice.
Alcaraz, W. A., Chen, E., Valdes, P., Kim, E., Lo, Y. H., Vo, J., and Hamilton, B. A. (2011)
Human Molecular Genetics
20, 3822-3830. (Cover article) [Free PMC]
Modifier genes for mouse phosphatidylinositol transfer protein alpha (vibrator) that bypass juvenile lethality.
Concepcion, D., Johannes, F., Lo, Y. H., Yao, J., Fong, J., and Hamilton, B. A. (2011)
Genetics
187, 1185-1191. [Free PMC]
Multipotent genetic suppression of retrotransposon-induced mutations by Nxf1 through fine-tuning of alternative splicing.
Concepcion, D., Flores-García, L., and Hamilton, B. A. (2009)
PLoS Genetics 5, e1000484
. [Open Access]
An ancestral variant of Secretogranin II confers regulation by PHOX2 transcription factors and association with hypertension.
Wen, G., Wessel, J., Zhou, W., Ehret, G. B., Rao, F., Stridsberg, M., Mahata, S. K., Gent, P. M., Das, M., Cooper, R. S., Chakravarti, A., Zhou, H., Schork, N. J., O'Connor, D. T., and Hamilton, B. A. (2007)
Human Molecular Genetics 16, 1752-1764. [Free PMC]
Zfp423 controls proliferation and differentiation of neural precursors in cerebellar vermis formation.
Alcaraz, W. A., Gold, D. A., Raponi, E. Gent, P. M., Concepcion, D., and Hamilton, B. A. (2006)
PNAS 103, 19424-19429. Supporting information [Free PMC]
RORa in genetic control of cerebellum development: 50 staggering years.(Review)
Gold, D. A., Gent, P. M., and Hamilton, B. A. (2007)
Brain Research 1140, 19-25. [published online January 19, 2006]
Nature Genetics mutant of the month for January, 2007
Mutation rate and predicted phenotypic target sizes in ENU-treated mice.
Concepcion, D., Seburn, K., Wen, G., Frankel, W. N., and Hamilton, B. A. (2004)
Genetics 168, 953-959. [Free PMC]
Both rare and common polymorphisms contribute functional variation at CHGA, a regulator of catecholamine physiology.
Wen, G., Mahata, S. K., Cadman, P., Mahata, M., Ghosh, S., Mahapatra, N. R., Rao, F., Stridsberg, M., Smith, D. W., Mahboubi, P., Schork, N. J., O'Connor, D. T., and Hamilton, B. A. (2004)
Am. J. Hum. Genetics 74, 197-207. [Free PMC]
A natural allele of Nxf1 suppresses retrovirus insertional mutations.
Floyd, J. A., Gold, D. A., Concepcion, D., Poon, T. H., Wang, X., Keithley, E., Chen, D., Ward, E. J., Chinn, S. B., Friedman, R. A., Yu, H.-T., Moriwaki, K., Shiroishi, T., and Hamilton, B. A. (2003)
Nature Genetics 35, 221-228. (Cover caption) [News&Views] [Free PMC]
Nature Genetics mutant of the month for August, 2007
RORa coordinates reciprocal signaling in cerebellar development through Sonic hedgehog and calcium-dependent pathways
Gold, D. A., Baek, S. H., Schork, N. J., Rose, D. W., Larsen, D. D., Sachs, B. D., Rosenfeld, M. G., and Hamilton, B. A. (2003)
Neuron 40, 1119-1131. [Free PMC]
Nature Genetics mutant of the month for January, 2007
a-Synuclein A53T substitution associated with Parkinson's Disease also marks the divergence of old world and new world primates.
Hamilton, B. A. (2003)
Genomics 83, 739-742.
Mice lacking phosphatidylinositol transfer protein alpha exhibit spinocerebellar degeneration, intestinal and hepatic steatosis, and hypoglycemia.
Alb, J. G. , Cortese, J. D. , Phillips, S. E., Albin, R. L., Nagy, T. R., Hamilton, B. A., and Bankaitis, V. A. (2003)
J. Biol. Chem. 278, 33501-18.
Variations in abundance: Genome-wide responses to genetic polymorphism and vice versa. (Minireview)
Hamilton, B. A. (2002)
Genome Biology 3, 1029.1-1029.3. [Free PMC]
Of Mice and Genome Sequence.(Minireview)
Hamilton, B. A. and Frankel, W. N. (2001)
Cell 107, 13-16.
The vibrator mutation causes neurodegeneration via reduced expression of PITPa: Positional complementation cloning and extragenic suppression.
Hamilton, B. A., Smith, D. J., Mueller, K. L., Kerrebrock, A. W., Bronson, R. T., van Berkel, V., Daly, M. J., Kruglyak, L., Reeve, M. P., Nemhauser, J. L., Hawkins, T. L., Rubin, E. M. and Lander, E. S. (1997)
Neuron 18, 711-722.
Nature Genetics mutant of the month for August, 2007
Disruption of nuclear hormone receptor RORa in staggerer mice.
Hamilton, B. A., Frankel, W. N., Kerrebrock, A. W., Hawkins, T. L., FitzHugh, W., Kusumi, K., Russell, L. B., van Berkel, V., Mueller, K. L., Birren, B. W., Kruglyak, L., and Lander, E. S. (1996)
Nature 379, 736-739.
Nature Genetics mutant of the month for January, 2007