Dr. Ghosh obtained her medical degree from Christian Medical College, Vellore, in India. She started her career in science under the mentorship of Stuart Kornfeld at Washington University in St. Louis, Missouri, before beginning her internship and residency in internal medicine and a postdoctoral training in the laboratory of Marilyn G. Farquhar here at UC San Diego. Her postdoctoral work has directly led to the characterization of a novel stratum in signal transduction by a unique class of molecules, which she christened “molecular rheostats”.
Since being appointed at UCSD, the Ghosh lab continues to investigate how G proteins and their modulators are regulated by receptor and non-receptor tyrosine kinases /phosphatases that are triggered by growth factors. Her lab strives to discover novel interfaces assembled at the crossroads of G protein and growth factor signaling pathways, and broadly translate their significance in a multitude of organ systems to study a variety of chronic diseases, e.g., diabetes, cancer metastasis, organ fibrosis; all of which are multi-receptor in origin and frustratingly incurable.
Pradipta Ghosh's Full Bio