Barbara Jung, MD

Barbara Jung

Dr. Jung received her MD and Doctorate in Medicine in 1996 from the Ludwig-Maximilians University, Munich, Germany. After a postdoctoral fellowship at the Sidney Kimmel Cancer Center in San Diego, she joined UC San Diego's Physician-Scientist Training Pathway in 1999, where she completed a residency in internal medicine followed by a fellowship in gastroenterology. In 2004, she accepted a faculty position here at UC San Diego as an assistant professor. She was awarded a K08 grant in 2005 and became Assistant Program Director for the Gastroenterology Fellowship Program in 2006. She continues her work on colon cancer growth factor signaling while remaining actively involved in clinical work as well as teaching.

Selected Publications

Vogt T, Welsh J, Stolz W, Kullmann F, Jung B, Landthaler M and McClelland M. (1997) RNA fingerprinting displays UVB-specific disruption of transcriptional control in human melanocytes. Cancer Res 57, 3554-3561.

Vogt T, Stolz W, Jung B, Welsh J, Kerbel RS, Landthaler M and McClelland M. (1998) Overexpression of Lerk-5/eplg5 messenger RNA : a novel marker for increased tumorigenicity and metatstatic potential in human malignant melanomas. Clin Cancer Res 4, 791-797.

Trenkle T, Welsh J, Jung B, Mathieu-Daude F, and McClelland M. (1998) Non-stoichiometric reduced complexity probes for cDNA arrays. Nucleic Acid Res 26(17), 3883-3891.

Jung B, Vogt T, Welsh J, McClelland M and Kullmann F. (1998) Estrogen-responsive RING finger mRNA induction in gastrointestinal carcinoma cells following bile acid and estrogen treatment. Carcinogenesis 19(11), 1901-1906.

Fotedar R, Brickner H, Saadatmandi N, Rousselle T, Diederich L, Munshi A, Jung B, Reed JC, and Fotedar A. (1999) Effect of p21waf1/cip1 transgene on radiation induced apoptosis in T cells. Oncogene 18, 3652-3658.

Chantalat L, Skoufias D, Kleman J-P, Jung B, Dideberg O, and Margolis R. (2000) Crystal Structure of human survivin reveals a bow tie-shaped dimer with two unusual alpha-helical extensions. Molecular Cell 6, 183-189.

Vogt T, McClelland M, Jung B, Popova S, Bogenrieder T, Becker B, Rumpler O, and Stolz W. (2001). Progression and NSAID-induced apoptosis in malignant melanoma is independent of cycloxygenase II. Melanoma Res 11(6), 587-599.

Lechner S, Mueller - Ladner U, Schlottmann K, Jung B, McClelland M, Rueschoff J, Welsh J, Schoelmerich J, and Kullmann F. (2002) Bile acids mimic oxidative stress induced upregulation of thioredoxin reductase in colon cancer cell lines. Carcinogenesis 23(8), 1281-1288.

Jung B and Carethers J (2003). Screening for colorectal cancer. Analysis of evidence and cost-effectiveness. J Clinical Outcomes Med 10(2), 87-94.

Jung B, Carethers J, Behling C, and Garvie J (2003). Aphthous colitis in a young male with diverticulitis. Gastrointest Endoscopy 58(2), 301-304.

Jung B, Steinbach J, Beaumont C, and Mittal R (2004). Discordance in esophageal acid sensitivity detected by prolonged pH monitoring and Bernstein testing. American J of Gastro 99(3):410-415 .

Jung B, Doctolero R, Tajima A, Nguyen AK, Keku T, Sandler RS, and Carethers JM (2004). Loss of activin receptor type 2 protein expression in microsatellite unstable colorectal cancers. Gastroenterology 126(3):654-659.

Jung B, Barbier V, Brickner H, Welsh J, Fotedar A, and McClelland M (2005). Mechanisms of sulindac-induced apoptosis and cell cycle arrest. Cancer Letters 219:15-25.

Jung B, Smith EJ, Doctolero RT, Gervaz P, Cerotttini JP, Bouzourene H, Goel A, Arnold CN, Boland CR, Alonso JC, Greenson JK, and Carethers JM (2006) Effects of growth factor receptor mutations on survival, stage, and histology of microsatellite unstable colorectal cancers. Int J Cancer, 118: 2509-2513

Beck SE, Jung B, Fiorino A, Gomez J, Del Rosario E, Cabrera BL, Huang SC Chow JYC, and Carethers JM. (2006) Bone morphogenetic protein signaling and growth suppression in colon cancer. Am J Physiology: GI & Liver Physiology, 291:135-145, 2006

Gosh P and Jung B. (2007) Giant Paraesophageal Hernia Causing Compression Pulmonary Atelectasis: Starved for Air when Satiated with Food. J Gastroenterol and Hepatology, In press