Paul Chi-Jen Cheng, MD, PhD

Paul Chi-Jen Cheng

Dr. Cheng completed his PhD and MD in 2002 at Northwestern University. In July of 2002, Dr. Cheng began his research residency training here at UC San Diego and began fellowship in the Division of Hematology-Oncology in 2004. He served as chief fellow in the division in 2007. He then became a postdoctoral research associate at the Salk Institute and worked with Dr. Tony Hunter in the Molecular and Cellular Biology Laboratory. 

Selected Publications

Cheng, P.C. and Wong, G. (1996) Honey bee propolis: prospects in medicine. Bee World 77(1): 8-15.

Peng, C.Y.S., Mussen, E., Fong, A., Cheng, P., Wong, G. and Montague, M.A. (1996) Laboratory and field studies on the effects of the antibiotic tylosin on honey bee Apis mellifera L. (Hymenoptera: Apidae) development and prevention of American Foulbrood Disease. J. Invert. Pathol. 67: 65-71.

Song, W., Cho, H., Cheng, P. and Pierce, S.K. (1995) Entry of B cell antigen receptor and antigen into class II peptide-loading compartment is independent of receptor cross-linking. J. Immunol. 155(9): 4255-4263.

Brown, B.K., Li, C., Cheng, P.C., and Song, W. (1999) Trafficking of the Ig/Ig� heterodimer with membrane Ig and bound antigen to the major histocompatibility complex class II peptide-loading compartment. J. Biol. Chem. 274: 11439-11446.

Cheng, P.C., Steele, C.R., Gu, L., Song, W., and Pierce, S.K. (1999) MHC class II antigen processing in B cells: Accelerated intracellular targeting of antigens. J. Immunol. 162: 7171-7180.

Wagle, N.M., Cheng, P., Kim, J., Sproul, T.W., Kausch, K.D., and Pierce, S.K. (1999) B-lymphocyte signaling receptors and the control of class-II antigen processing. Curr. Top. Microbiol. Immunol. 254: 106-126.

Cheng, P.C., Dykstra, M.L., Mitchell, R.N., and Pierce, S.K. (1999) A role for lipid rafts in BCR signaling and antigen targeting. J. Exp. Med. 190: 1549-1560.

Sproul T.W., Cheng P.C., Dykstra M.L., Pierce S.K. (2000) A role for MHC class II antigen processing in B cell development. Int. Rev. Immunol. 19(2-3):139-155.

Cherukuri A., Cheng P.C., Sohn H.W., Pierce S.K. (2001) The CD19/CD21 complex functions to prolong B cell antigen receptor signaling from lipid rafts. Immunity. 14(2): 169-179.

Cheng P.C., Brown B.K., Song W., and Pierce S.K. (2001) Translocation of the B cell antigen receptor into lipid rafts reveals a novel step in signaling. J. Immunol. 166: 3693-3701.

Cheng, P.C., Cherukuri, A., Dykstra, M., Malapati, S., Sproul, T., Chen, M.R., and Pierce, S.K. (2001) Floating the raft hypothesis: The roles of lipid rafts in B cell antigen receptor function. Semin. Immunol. 13:107-114.

Cherukuri, A., Cheng, P.C., and Pierce, S.K. (2001) The Role of the CD19/CD21 Complex in B Cell Processing and Presentation of Complement-Tagged Antigens. J. Immunol. 167: 163-172.