Publications

Alkhouri N, Carter-Kent C, Elias M, Feldstein AE. Atherogenic dyslipidemia and cardiovascular risk in children with nonalcoholic fatty liver disease. Clin Lipidol, 2011, in press.

Alkhouri N, De Vito R, Alisi A, Yerian L, Lopez R, Feldstein AE, Nobili V. Development and Validation of a New Histological Score for Pediatric Nonalcoholic Fatty Liver Disease (NAFLD). J Hepatol, 2012 Aug 4 [Epub ahead of print].

Alkhouri N, Feldstein AE. The TONIC trial: A step forward in treating pediatric nonalcoholic fatty liver disease. Hepatology, 55(4):1292-5, 2012.

Alkhouri N, Sedki E, Alisi A, Lopez R, Pinzani M, Feldstein AE, Nobili V. Combined paediatric NAFLD fibrosis index and transient elastography to predict clinically significant fibrosis in children with fatty liver disease. Liver Int, 33(1):79-85, 2013.

Aufreiter S, Kim JH, O’Connor DL. Dietary oligosaccharides increase colonic weight and the amount but not concentration of bacterially synthesized folate in the colon of piglets. J Nutr, 141(3):366-372, 2011.

Awai HI, Yu EL, Ellis LS, Schwimmer JB. Liver toxicity of anabolic androgenic steroid use in an adolescent with nonalcoholic fatty liver disease. J Pediatr Gastroenterol Nutr. 2013 Apr 4 (epub).

Barshop NJ, Capparelli EV, Sirlin CB, Schwimmer JB, Lavine JE. Acetaminophen pharmacokinetics in children with nonalcoholic fatty liver disease. Journal of Pediatric Gastroenterology and Nutrition, 52(2):198-202, 2011.

Bode L Human milk oligosaccharides: Every baby needs a sugar mama. Glycobiology, 22:1147-62, 2012.

Bode L, Kuhn L, Kim HY, Hsiao L, Nissan C, Sinkala M, Kankasa C, Mwiya M, Thea DM, Aldrovandi GM. Human milk oligosaccharide concentration and risk of postnatal transmission of HIV through breastfeeding. Am J Clin Nutr, 96:831-9, 2012.

Boutelle KN, Cafri G, Crow SJ. A parent-only intervention for childhood obesity. Obesity, 19(3), 574–580, 2011.

Brunt EM, Kleiner DE, Wilson LA, Belt P, Neuschwander-Tetri BA; NASH Clinical Research Network (CRN). Nonalcoholic fatty liver disease (NAFLD) activity score and the histopathologic diagnosis in NAFLD: Distinct clinicopathologic meanings. Hepatology, 53(3):810-820, 2011.

Choi LJ, Huang JS. A pilot study of S-Adenosyl-Methionine in treatment of functional abdominal pain in children. Altern Health and Med, 19(5): 61-4, 2013.

Choi, LJ, Montez K. What are the common gastrointestinal diseases associated with childhood obesity? In: Curbside Consultation in Pediatric Obesity. Roth, J.R. and Bousvaros, eds., Thorofare, New Jersey: SLACK Incorporated, 2013 (in press).

Dixon LJ, Berk M, Thapaliya S, Papouchado BG, Feldstein AE. Caspase-1-mediated regulation of fibrogenesis in diet-induced steatohepatitis. Lab Invest, 2012 Mar 12. doi: 10.1038/labinvest.2012.45 [Epub ahead of print].

Dixon LJ, Flask CA, Papouchado BG, Feldstein AE, Nagy LE. Caspase-1 as a central regulator of high fat diet-induced non-alcoholic steatohepatitis. PLoS One, 8(2):e56100, 2013, doi: 10.1371/journal.pone.0056100. Epub 2013 Feb 7.

Dohil R, Aceves SS, Dohil MA. Oral viscous budesonide therapy in children with epidermolyisis bullosa and proximal esophageal strictures. JPGN (in press).

Dohil R, Schmeltzer S, Cabrera BL, Wang T, Durelle J, Duke KB, Schwimmer JB, Lavine JE. Enteric-coated cysteamine for the treatment of paediatric non-alcoholic fatty liver disease. Alimentary Pharmacology & Therapeutics, 33(9):1036-44, 2011.

Dohil R, Meyer, L, Schmelzer S, Cabrera B, Lavine J, Phillips S. The effect of cysteamine bitartrate on adiponectin multimerization in non-alcoholic fatty liver disease and healthy subjects. J Pediatr, 161:639-45, 2012.

Dohil R, Cabrera B, Gangoiti J, Barshop B, Rioux P. Pharmacokinetics of cysteamine bitartrate following intra-duodenal delivery in rats. Fundam Clin Pharmacol 2012; Oct 31 (E-print ahead of press).

Dohil, R, Cabrera B, Gangoiti J, Rioux P. The effect of food on cysteamine bitartrate absorption in healthy subjects. Clinical Pharmacology in Drug Development, 2012 (E-print ahead of press).

Dohil R, Cabrera B. Treatment of cystinosis with delayed-release cysteamine – six year follow-up. Pediatric Nephology, 28: 507-10, 2013.

Duvvuri V, Cromley T, Klabunde M, Boutelle K, Kaye WH. Differential weight restoration on olanzapine versus fluoxetine in identical twins with anorexia nervosa. International Journal of Eating Disorders, DOI: 10.1002/eat.20917, 2011.

Eguchi A, Feldstein AE. Lysosomal Cathepsin D contributes to cell death during adipocyte hypertrophy. Adipocyte, 2013 July.

Feldstein AE. Fatty liver disease in children. In: Nonalcoholic Fatty Liver Disease: Clinical Management,Wiley-Blackwell, editors: G Farrell, C Day, A McCullough, 2012.

Fleming SE, Kim JH. Ultrasound-guided umbilical catheter insertion in neonates. J Perinatol, 31(5):344-349, 2011.

Fulkerson JA, Kubik MY, Rydell S, Boutelle KN, Story M, Neumark-Sztainer D. Focus groups with working parents of school-aged children: What’s needed to improve family meals? Journal of Nutrition, Education and Behavior, 43(3)189-193, 2011.

Gornicka A, Fettig J, Eguchi A, Berk MP, Thapaliya S, Dixon LJ, Feldstein AE. Adipocyte hypertrophy is associated with lysosomal permeability both in vivo and in vitro: Role in adipose tissue inflammation. Am J Physiol Endocrinol Metab, 2012 Jun 26 [Epub ahead of print].

Goyal NP, Schwimmer JB. What co-morbidities should I screen for in my patient who is obese? In: Curbside Consults (in press 2012).

Grant PM, Kitch D, McComsey GA, Dube M, Haubrich R, Huang JS, Riddler S, Tebas P, Zolopa AR, Collier A, Brown TT. Lower baseline CD4+ Count is associated with greater bone mineral density loss after ART initiation. Clin Infect Dis 2013 (in press).

Guerrerio AL, Colvin RM, Schwartz AK, Molleston JP, Murray KF, Diehl A, Mohan P, Schwimmer JB, Lavine JE, Torbenson MS, Scheimann AO. "Choline intake in a large cohort of patients with nonalcoholic fatty liver disease." Am J Clin Nutr, 95(4):892-900, 2012.

Huang JS, Tobin A, Harvey L, Nelson TR. Diagnostic medical radiation in pediatric patients with inflammatory bowel disease. J Pediatr Gastroenterol Nutr, 53(5): 502-6, 2011.

Huang JS, Gottschalk M, Norman GJ, Calfas KJ, Sallis JF, Patrick K. Compliance with behavioral guidelines for diet, physical activity and sedentary behaviors is related to insulin resistance among overweight and obese youth. BMC Research Notes, 4:29, 2011.

Huang JS, Gottschalk M, Pian M, Dillon L, Barajas D, Bartholomew LK. Transition to adult care: Systematic assessment of adolescents with a chronic illness and their medical teams. J Pediatr, 159(6): 994-8, 2011.

Huang JS, Tobin A, Tompane T. Clinicians poorly assess health literacy-related readiness for transition to adult care in adolescents with inflammatory bowel disease. Clin Gastroenterol Hepatol, 10: 626-32, 2012.

Huang JS, Barlow SE, Quiros-Tejeira RE, Scheimann A, Skelton J, Suskind D, Tsai P, Uko V, Warolin JP, Xanthakos SA: The NASPGHAN Obesity Task Force. Consensus Statement: Childhood Obesity for Pediatric Gastroenterologists. J Pediatr Gastroenterol Nutr, 56(1):99-109, 2013.

Huang JS, Chun S, Sandhu A, Terrones L. Quality improvement in childhood obesity management through the maintenance of certification process. J Pediatr, 2013 (in press).

Huang JS, Hughes MD, Riddler SA, Haubrich RH. Bone mineral density effects of randomized regimen and nucleoside reverse transcriptase inhibitor (NRTI) selection from ACTG A5142. HIV Clinical Trials (in press).

Huang SC, Lee, JK, Smith J, Doctolero RT, Tajima A, Beck SE, Weidner N, Carethers JM. Evidence for an hMSH3 defect in familial hamartomatous polyps. Cancer, 117(3):492-500, 2011.

Huh D, Stice E, Shaw H, Boutelle K. Female overweight and obesity in adolescence: developmental trends and ethnic differences in prevalence, incidence, and remission. Journal Of Youth And Adolescence, DOI: 10.1007/s 10964-011-9664.

Iwaisako K, Haimerl M, Paik YH, Taura K, Kodama Y, Sirlin C, Yu E, Yu RT, Downes M, Evans RM, Brenner DA, Schnabl B. Protection from liver fibrosis by a peroxisome proliferator-activated receptor  agonist. Proc Natl Acad Sci USA, 2012 May 22; 109(21): E1369-76. Epub 2012 Apr 25.

Jantscher-Krenn E and Bode L (2012) Structure-function relationships of human milk oligosaccharides. Adv Nutr, 3:383S-91S.

Johnson BL, Schroeder ME, Wolfson T, Gamst AC, Hamilton G, Shiehmorteza M, Loomba R, Schwimmer JB, Reeder S, Middleton MS, Sirlin CB. Effect of flip angle on the accuracy and repeatability of hepatic proton density fat fraction estimation by complex data-based, T1-independent, T2-corrected, spectrum-modeled MRI. J Magn Reson Imaging, 2013 Apr 17 (Epub ahead of print).

Kim G, Giannini C, Pierpont B, Feldstein AE, Santoro N, Kursawe R, Shaw M, Duran E, Goldberg R, Dziura J, and Caprio S. Longitudinal Effects of MRI Measured Hepatic Steatosis on Biomarkers of Glucose Homeostasis and Hepatic Apoptosis in Obese Youth. Diabetes Care, 2012 Aug 28. [Epub ahead of print].

Kistler KD, Brunt EM, Clark JM, Diehl AM, Sallis JF, and Schwimmer JB for the NASH CRN Research Group. Physical activity recommendations, exercise intensity, and histological severity of nonalcoholic fatty liver disease. American Journal of Gastroenterology, 106(3):460-8, 2011.

Knatz S, Manginot T, Neumark-Sztainer D, Story M, Boutelle KN. Prevalence and psychosocial associations of secretive eating in adolescents. Childhood Obesity, 7(1): 30-35, 2011.

Lavine JE, Schwimmer JB, Van Natta ML, Molleston JP, Murray KF, Rosenthal P, Abrams SH, Scheimann AO, Sanyal AJ, Chalasani N, Tonascia J, Ünalp A, Clark JM, Brunt EM, Kleiner DE, Hoofnagle JH, Robuck PR, Nonalcoholic Steatohepatitis Clinical Research Network. Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trial. Journal of the American Medical Association, 305(16):1659-68, 2011.

Manthey CF, Autran CA, Eckmann L, Bode L (Human Milk Oligosaccharides protect against enteropathogenic E. coli attachment in vitro and colonization in suckling mice. J Pediatr Gastroenterol Nutr, 2013 (in press).

Meier P and Bode L Health, nutrition and cost outcomes of human milk feedings for very low birthweight infants. Adv Nutr, 2013 (in press).

Newton KN, Schwimmer JB. What should I do with an obese child who has elevated liver function test? In: Curbside Consults, 2013 (in press).

Preuss J, Maloney P, Peddibhotla S, Hedrick MP, Hershberger P, Gosalia P, Milewski M, Li YL, Sugarman E, Hood B, Suyama E, Nguyen K, Vasile S, Sergienko E, Mangravita-Novo A, Vicchiarelli M, McAnally D, Smith LH, Roth GP, Diwan J, Chung TDY, Jortzik E, Rahlfs S, Becker K, Pinkerton AB, Bode L. Discovery of a Plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase inhibitor (R,Z)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-(2-fluorobenzylidene)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxamide (ML276) that reduces parasite growth in vitro. J Med Chem, 55: 7262-72, 2012.

 

Puri K, Nobili V, Melville K, Corte CD, Sartorelli MR, Lopez R, Feldstein AE, Alkhouri N. Serum bilirubin level is inversely associated with nonalcoholic steatohepatitis in children. J Pediatr Gastroenterol Nutr. 2013 Mar 19, [Epub ahead of print].

Ramos GA, Hanley AA, Aguayo J, Warshak CR, Kim JH, Moore TR. Neonatal chemical hypoglycemia in newborns from pregnancies complicated by type 2 and gestational diabetes mellitus - the importance of neonatal ponderal index. J Matern Fetal Neonatal Med, epub 2011.

Rockwell RE, Boutelle K, Trunko ME, Jacobs MJ, Kaye WH. An innovative short-term, intensive, family-based treatment for adolescent anorexia nervosa: Case series. European Eating Disorders Review, DOI: 10.1002/erv.1094, 2011.

Sauer CW, Kim JH. Human milk macronutrient analysis using point-of-care near-infrared spectrophotometry. J Perinatol, 31(5):339-343, 2011.

Schnell U, Kuipers J, Mueller JL, Veenstra-Algra A, Sivagnanam M, Giepmans BN. Absence of cell-surface EpCAM in congenital tufting enteropathy. Hum Mol Genet. 2013 Mar 15.

Schwimmer JB. Clinical Trials for adolescent obesity: Cooking up an alphabet stew of what to do. JAMA Pediatrics 167(4):391-3, 2013.

Shannon A, Alkhouri N, Carter-Kent C, Monti L, Devito R, Lopez R, Feldstein AE., Nobili V. Ultrasonographic quantitative estimation of hepatic steatosis in children with nonalcoholic fatty liver disease (nafld): A prospective study. J Pediatr Gastroenterol Nutr, 2011 (in press).

Sivagnanam M, Mueller J, Szigeti R, Gopalakrishna GS, Finegold MJ, Kellermayer R. Aminoglycoside therapy of nonsense mutation induced intestinal failure. Pediatrics (in review).

Sivagnanam M, Mueller JL, Szigeti R, Gopalakrishna GS, Kellermayer R. Transcriptional read-through induction treatment trial in intestinal failure induced by an EpCAM nonsense mutation. Case Report Med, 2012:173195. Epub 2012 Sep 9.

Sivagnanam M, Janecke AR, Müller T, Heinz-Erian P, Taylor S, Bird LM. Case of syndromic tufting enteropathy harbors SPINT2 mutation seen in congenital sodium diarrhea. 6.

Suzuki A, Abdelmalek MF, Schwimmer JB, Lavine JE, Scheimann A, Unalp-Arida A, Yates K, Sanyal A, Guy CD, Diehl AM; NASH CRN. Association between puberty and features of nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol, 10(7):786-94, 2012.

Swiderska-Syn M, Suzuki A, Guy CD, Schwimmer JB, Abdelmalek MF, Lavine JE, Diehl AM. Hedgehog pathway and pediatric nonalcoholic fatty liver disease. Hepatology, 57(5):1814-2520, 2013.

Tompane TM, Bush R, Dansky T, Huang JS. Diagnostic imaging studies performed in children over a nine-year period. Pediatrics, 131(1):e45-52, 2013.

Tompane TM, Leong CW, Bush R, Chuang N, Dansky T, Huang JS. The appropriateness of radiology procedures performed in children with gastrointestinal symptoms and conditions. Clin Gastroenterol Hepatol, 2013 (in press).

Walker RW, Le K, Davis J, Alderete T., Cherry R, Lebel S, Goran MI. High rates of fructose malabsorption are associated with reduced liver fat in obese African Americans. J American College of Nutrition, 31:369–374, 2012.

Vos MB, Colvin R, Belt P, Molleston JP, Murray KF, Rosenthal P, Schwimmer JB, Tonascia J, Unalp A, Lavine JE; NASH CRN Research Group. Correlation of vitamin E, uric acid, and diet composition with histologic features of pediatric NAFLD. J Pediatr Gastroenterol Nutr, 54(1):90-6, 2012.

Wang Z, Klipfell E, Bennett BJ, Koeth R, Levison B, DuGar B, Feldstein AE, Britt EB, Fu X, Chung YM, Schauer P, Smith JD, Allayee H, Tang W, DiDonato JA, Lusis AJ, and Hazen SL. Gut flora dependent metabolism of dietary phosphatidylcholine contributes to cardiovascular disease. Nature, 472(7341):57-63, 2011.

Yin MT, Kendall MA, Wu X, Tassiopoulos K, Hochberg M, Huang JS, Glesby MJ, Bolivar H, McComsey GA. Fractures after antiretroviral initiation: An analysis of the ACTG longitudinal linked randomized trial (ALLRT) study. AIDS, 26(17):2175-84, 2012.

Yokoo T, Bydder M, Hamilton G, Middleton MS, Gamst AC, Wolfson T, Patton HM, Lavine JE, Schwimmer JB, Sirlin CB. Estimation of hepatic proton-density fat fraction by magnetic resonance imaging at 3T. Radiology, 258(3):749-59, 2011.

Yu E, Schwimmer JB, Lavine JE. Other acquired liver disease, non-alcoholic fatty liver disease and steatohepatits. The NASPGHAN Fellows Concise Review of Pediatric Gastroenterology, Hepatology and Nutrition. Sondheimer JM and Waasdorp Hurtado C. Castle Connolly Graduate Medical Publishing, Ltd., pg. 335-337, 2011.

Yu EL. Inflammatory bowel disease. Pediatric Acute Care: A Guide for Interprofessional Practice, Reuter-Rice, K and Bolick B. Burlington, MA: Jones & Bartlett Learning, pg: 535-540, 2011.

Yang N, Garcia MA, Quinton PM. Normal mucus formation requires cAMP-dependent HCO3-secretion and ca2+-mediated mucin exocytosis. Journal of Physiology, 2013 Jul 29. [Epub ahead of print].