Publications

Ali SS, Hsiao Y, Zhao HW, Dugan LL, Haddad GG, Zhou D. Hypoxia-adaptation involves mitochondrial metabolic depression and decreased ROS leakage. 2012. PLoS ONE, 7(5):e36801. PMID: 22574227.

Arnold JC, Cannavino CR, Ross MK, Westley B, Miller T, Riffenburg R, Bradley J. Acute Bacterial Osteoarticular Infections: Eight Year Review of Outcomes Using Oral Step-down Therapy. Manuscript 2012-0220. Pediatrics, vol 130, number 4, October 2012.

Azad P, Ryu J, Haddad GG, Distinct role of Hsp70 in drosophila hemocytes during severe hypoxia. Free Radical Biology and Medicine, 51(2): 530-538, 2011.

Azad P, Zhou D, Zarndt R, Haddad GG. Identification of genes underlying hypoxia tolerance in drosophila by a P-element screen. G3 (Bethesda). 2(10): 1169–1178, 2012. PMCID: PMC3464109

Azad P, Haddad GG. Genetic animal models of preconditioning. Transl Stroke Res, 4(1):51-55, 2013. PMCID:PMC3614364.

Bradley JE, Chan JM, Hagood JS. Effect of the GPI anchor of human Thy-1 on antibody recognition and function. Lab Invest. 93(3):365-74, 2013.

Cisneros J, Hagood J, Checa M, Ortiz-Quintero B, Negreros M, Herrera I, Ramos C, Pardo A, Selman M. Hypermethylation-mediated silencing of p14(ARF) in fibroblasts from idiopathic pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol, 303(4):L295-303, 2012.

Cooper, JL, P Quinton, and S. Ballard 2013. Mucociliary transport in porcine trachea: differential effects of inhibiting chloride and bicarbonate secretion. Am J Physiol Lung Cell Mol Physiol, 304:L184-190.

Dell S, Cernelc-Kohan M, Hagood JS. Diffuse and interstitial lung disease and childhood rheumatologic disorders. Curr Opin Rheumatol, 24(5):530-40, 2012. Invited review.

Douglas, RM, Chen A, Iniguez A, Wang J, Fu Z, Powell FL Jr, Haddad G G, Yao H. Chemokine receptor-like 2 is involved in ischemic brain injury. J Exp Stroke Transl Med, 6:1-6, 2013. PMCID:PMC3705577.

Felfly H, Zambon AC, Xue J, Muotri A, Zhou D, Snyder E, Haddad GG. Severe hypoxia: Consequences to neural stem cells and neurons. Journal of Neurology Research, 1(5):177-189, 2011.

Felfly H, Xue J, Zambon AC, Muotri A, Zhou D, Haddad GG. Identification of a neuronal gene expression signature: role of cell-cycle arrest in murine neuronal differentiation in vitro. American Journal of Physiology Regulatory, Integrative and Comparative Physiology, 301(3):R727-45, 2011.

Felfly H, Haddad GG. Protection of mice from stroke using hematopoietic stem cell transplantation. Stem Cells and Cancer Stem Cells, Volume 3. Hayat MA, Ed. Springer, 2012, pp. 295-303.

Felfly H, Haddad GG. Hematopoietic Stem Cells: Potential New Applications for Translational Medicine. In: Hematopoietic Stem Cells: New Research, Nova Science Publishers, Inc. 2012, pp. 51-96.

Haddad GG. Development of the lung and respiratory system. In: Textbook of Clinical Pediatrics, 2nd Edition. Edited by AY Elzouki, HA Harfi and H Nazer, FB Stapleton, W Oh, RH Whitley. Springer, 2012, pp. 2125-2128.

Haddad GG. Pulmonary function testing. In: Textbook of Clinical Pediatrics, 2nd Edition. Edited by AY Elzouki, HA Harfi and H Nazer, FB Stapleton, W Oh, RH Whitley. Springer, 2012, pp. 2133-2135.

Haddad GG. The pathophysiology of cough. In: Textbook of Clinical Pediatrics, 2nd Edition. Edited by AY Elzouki, HA Harfi and H Nazer, FB Stapleton, W Oh, RH Whitley. Springer, 2012, pp. 2149-2151.

Haddad GG. Upper airway obstruction and hypoventilation during sleep. In: Textbook of Clinical Pediatrics, 2nd Edition. Edited by AY Elzouki, HA Harfi and H Nazer, FB Stapleton, W Oh, RH Whitley. Springer, 2012, pp. 2221-2224.

Haddad GG. Primary Ciliary Dyskinesia. In: Textbook of Clinical Pediatrics, 2nd Edition. Edited by AY Elzouki, HA Harfi and H Nazer, FB Stapleton, W Oh, RH Whitley. Springer, 2012, pp. 2225-2227.

Hagood JS, Ambalavanan N. Systems biology of lung development and regeneration: current knowledge and recommendations for future research. Wiley Interdiscip Rev Syst Biol Med. 2013 Mar-Apr;5(2):125-33.

Hamvas A, Deterding R, Balch W, Schwartz D, Albertine KH, Whitsett JA, Cardoso WV, Kotton DN, Kourembanas S, Hagood JS. Diffuse Lung Disease in Children: Summary of a Scientific Conference. Pediatr Pulmonol. 2013 Jun 24. doi: 10.1002/ppul.22805. [Epub ahead of print]

Huang W, Vayalil PK, Miyata T, Hagood J, and Liu R-M. Therapeutic value of small molecule inhibitor to plasminogen activator inhibitor-1 for lung fibrosis. Am J Respir Cell Mol Biol. 2012 Jan;46(1):87-95.

Heinrichsen E, Haddad GG. Role of High-fat Diet in Stress Response in Drosophila. 2012. PLos ONE, 7(8):e42587. PMCID:PMC3411628.

Kinney HC, Rognum TO, Nattie EE, Haddad GG, Hyma B, McEntire B, Paterson DS, Crandall L, Byard RW. Sudden and Unexpected Death in Early Life: Proceedings of a Symposium in Honor of Dr. Henry F. Krous 2012. Forensic Science, Medicine and Pathology, 8(4):414-25 PMID:22941540.

Kis K, Liu X, Hagood JS. Myofibroblast differentiation and survival in fibrotic disease. Expert Rev Mol Med, 2011 Aug 23;13:e27. PMID:21861939.

Lesser DJ, Haddad GG, Bush RA, Pian MS. The utility of a portable recording device for screening of obstructive sleep apnea in obese adolescents. J. Clin Sleep Med, 8(3):271-7, 2012. PMCID:PMC3365085.

Mittal M, Gu XQ, Pak O, Pamenter ME, Haag D, Fuchs B, Schermuly RT, Ghofrani HA, Brandes RP, Seeger W, Grimminger F, Haddad GG, Weissmann N. Hypoxia induces Kv channel current inhibition by increased NADPH oxidase derived reactive oxygen species. Free Radical Biology & Medicine, 52(6):1033-42, 2012. PMID: 22222468.

Nuovo GR, Hagood JS, Magro CM, Chin N, Kapil R, Davis L, Marsh CB, and Folcik VA. The distribution of immunomodulatory cells in the lungs of patients with idiopathic pulmonary fibrosis. Modern Pathology, 25(3):416-33, 2012.

Pamenter ME, Ali SS, Tang Q, Finley CJ, Gu X, Dugan LL, Haddad GG. An in vitro ischemic penumbral mimic perfusate increases NADPH oxidase-mediated superoxide production in cultured hippocampal neurons. 2011. Brain Res, 3;1452:165-72, 2012. PMCID:PMC3326196. Pamenter ME, Hogg DW, Gu XQ, Buck LT, Haddad GG. Painted turtle cortex is resistant to an in vitro mimic of the ischemic mammalian penumbra. J Cereb Blood Flow Metab, 32(11):2033- 43, 2012. PMCID: PMC3493991

Pamenter ME, Ryu J, Hua S, Perkins G, Mendiola V, Gu XQ, Ellisman MH, Haddad GG. 2012. DIDS prevents ischemic membrane degradation in cultured hippocampal neurons by inhibiting matrix metalloproteinase release. PLoS ONE, 7(8):e43995, 2012. PMCID: PMC3427179.

Pamenter ME, Perkins GA, McGinness AK, Gu XQ, Ellisman MG, Haddad GG. Autophagy and apoptosis are differentially induced in neurons and astrocytes treated with an in vitro mimic of the ischemic penumbra. PLoS ONE, 7(12):e51469, 2012. PMCID: PMC3520810.

Pamenter, M, Perkins, G, Gu, X, Ellisman, M, Haddad, G.G. DIDS (4,4-diisothiocyan atostilbenedisulphonic acid) induces apoptotic cell death in a hippocampal neuronal cell line and is not neuroprotective against ischemic stress. PLoS One, 8(4):e60804, 2013. PMCID:PMC3618322.

Perkins G, Hsiao YH, Yin S, Tjong J, Tran MT, Lau J, Xue J, Liu S, Ellisman MH, Zhou D. Ultrastructural modifications in the mitochondria of hypoxia-adapted Drosophila melanogaster. PLoS One, 7(9):e45344, 2012.

Powell F, Heldt G, Haddad GG. Chapter 41: Respiratory Physiology. Rogers¹ Textbook of Pediatric Critical Care, 2013 in press.

Quinton P, Molyneux M, Ip W, Dupuis A, Avolio J, Tullis E, Conrad D, Shamsuddin AK, Durie P, Gonska T. Beta-adrenergic Sweat Secretion as a Diagnostic Test for Cystic Fibrosis. Am J Respir Crit Care Med., 186 : 732–739, 2012.

Riordan J, Boucher R, Quinton PM. Eds. Cystic Fibrosis: A Trilogy of Biochemistry, Physiology, and Therapy. Cold Spring Harbor Laboratory Press, 340 pages, 2013.

Ross MK, Ellis L, Bird LM, Hagood JS. Pulmonary Interstitial Glycogenosis in a Patient Ultimately Diagnosed with Noonan Syndrome. Pediatr Pulmonol, 2013. Ryu J, Haddad GG, Carlo WA. Chapter 16: Clinical Effectiveness and Safety of Permissive Hypercapnea. Clin Perinatol, 39(3):603-12, 2012. 

Sanders YY, Ambalavanan N, Halloran B, Zhang X, Liu H, Crossman DK, Bray M, Zhang K, Thannickal VJ, Hagood JS. Am J Respir Crit Care Med, 186(6):525-35, 2012. Featured in editorial. Selected for Faculty of 1000.

Sieck GC, Haddad GG, Lucchesi P. Physiology’s impact: discovering life. Physiology (Bethesda), 28(2):62-3, 2013.

Shamsuddin, AK, and PM Quinton. 2012. Surface fluid absorption and secretion in small airways. J Physiol, 590:3561-3574, 2012.

Stucky E, Haddad GG. Respiratory Failure. In: Textbook of Clinical Pediatrics, 2nd Edition. Edited by AY Elzouki, HA Harfi and H Nazer, FB Stapleton, W Oh, RH Whitley. Springer, 2012, pp. 2141-2148.

Stokes DC, McBride JT, Hagood JS, Lesser DJ, Taylor JB. The (Pediatric Pulmonary) World Is Flat. The Spread of Internet-based Pediatric Pulmonary Case Conferences. Ann Am Thorac Soc, 10(3):274-5, 2013. doi: 10.1513/AnnalsATS.201301-005LE

Thannickal VJ, Hagood JS. Biological insights from clinical trials and networks. Am J Respir Crit Care Med, 185(5):475-6, 2012.

Udpa N, Zhou D, Haddad GG, Bafna V. Tests of selection in pooled case-control data: An empirical study. Front Genet, 2011. 2:83 PMCID: PMC3268381.

Varisco BM, Ambalavanan N, Hagood JS. Thy-1 Signals through PPARγ to Promote Pulmonary Lipofibroblast Differentiation in the Developing Lung. August 2011. Am J Respir Cell Mol Biol, 46(6):765-72, 2012.

Xie L, Ali T, Valencia R, Ferreira BL, Xue V, Tanweer M, Zhou D, Haddad GG, Bourne PE, Xie L. Multiscale Modeling of the Causal Functional Roles of nsSNPs in a Genome-Wide Association Study: Application to Hypoxia. 2013. BMC Genomics, 14 Suppl 3:S9 PMCID:PMC3665574.

Yin SY, Xue J, Sun HD, Wen B, Wang QH, Perkins G, Zhao HW, Ellisman MH, Hsiao Y, Yin L, Xie YY, Zi J, Lin L, Haddad GG, Zhou D, Liu SQ (2013). Quantitative Evaluation of the Mitochondrial Proteomes of Drosophila melanogaster Adapted to Extreme Oxygen Conditions" PLoS ONE. in press.

Zhao HW, Ali SS, Haddad GG. Does hyperoxia selection cause adaptive alterations of mitochondrial electron transport chain activity leading to a reduction of superoxide production? Antioxidants & Redox Signaling, 16(10):1071-6, 2012. PMCID:PMC3315163

Zhou, D, Udpa N, Gersten M, Visk DW, Bashir A, Xue J, Frazer K, Posakony J, Subramaniam S, Bafna V, Haddad GG. Experimental Selection of Hypoxia-tolerant Drosophila melanogaster. Proc Natl Acad Sci USA, 108(6): 2349-2354, 2011.

Zhou D, Udpa N, Ronen R, Stobdan T, Liang J, Appenzeller O, Zhao H, Yin Y, Du Y, Gu L, Cao R, Wang Y, Jin X, Huang C, Jia W, Cao D, Guo G, Gamboa J, Villafuerte F, Callacond D, Xue J, Liu S, Frazer K, Li Y, Bafna V, Haddad GG. Whole-Genome Sequencing Uncovers the Genetic Basis of Chronic Mountain Sickness in Andean Highlanders. The American Journal of Human Genetics, 93:1–11, 2013. Zhou D, Haddad GG. Genetic Analysis of Hypoxia Tolerance and Susceptibility in Drosophila and Humans. Annu Rev Genomics Hum Genet, 2013 Jun 26 PMID:23808366.