MEET THE PDRC RESEARCH TEAM

Maike Sander 5_2014.jpeg Maike Sander, MD: Beta Cell/Stem Cell Research
Dr. Sander is the director of the Pediatric Diabetes Research Center.  She is a professor in the UC San Diego's Departments of Pediatrics and Cellular & Molecular Medicine. Dr. Sander's research aims to understand how insulin-producing beta cells regenerate and function. Her laboratory has collaborated with Viacyte Inc. to develop strategies for generating replacement insulin-producing cells from stem cells for transplantation into patients. Stem cell-derived beta cells are currently being tested at UC San Diego in the first ever stem cell-based clinical trial for treatment of T1D.  More about Dr. Sander

michael-gottschalk-md-phd_cropped.jpg Michael Gottschalk, MD, PhD: Clinical Care and Clinical Research
Dr. Gottschalk is the associate director of the Pediatric Diabetes Research Center.  He is chief of pediatric endocrinology at Rady Children's Hospital and a clinical professor in the Department of Pediatrics at UC San Diego. In collaboration with immunologists, Dr. Gottschalk investigates the change in T-cell populations during the early phase of diabetes to identify potential biomarkers. He is also working to understand which regulatory T-cell populations are effective in suppressing autoimmune T-cells that are targeted against beta cells.  More about Dr. Gottschalk

WenxianFu_formal.jpg Wenxian Fu, PhD: Immunology Research
Dr. Fu is an assistant professor in the Department of Pediatrics at UC San Diego. He investigates the immune regulatory mechanisms that lead to type 1 diabetes (T1D) with the goal of discovering new preventive and therapeutic strategies. Dr. Fu is also exploring new imaging methods, such as Magnetic Resonance Imaging (MRI), for predicting the risk of developing T1D before patients are diagnosed with  the disease. More about Dr. Fu

Kyle J. Gaulton, PhD: Genetics Research
Dr. Gaulton comes from the Department of Genetics at Stanford University and arrived at the PDRC in January 2016.  Dr. Gaulton studies how genetic risk contributes to T1D. He works closely with scientists and clinicians at the Rady Pediatric Genomics and Systems Medicine Institute. His research will help identify novel strategies for preserving beta cells in patients at risk for T1D. More about Dr. Gaulton.

Ulupi_at desk_cropped.jpg

Ulupi Jhala, PhD: Beta Cell Research
Dr. Jhala is an associate professor at UC San Diego's Department of Pediatrics. The Jhala lab has two parallel research interests. The first is focused on understanding the mechanisms that regulate beta cell death in T1D. The second area of interest centers on identifying biomarkers for predicting T1D before patients are diagnosed. The hope is to intervene early to prevent beta cell loss. More about Dr. Jhala

Jkim.pngJane Kim, MD: Clinical Research
Dr. Kim is an assistant professor at UCSD's Department of Pediatrics and a physician-scientist in the UCSD Division of Pediatric Endocrinology. Her clinical translational research aims to identify early biomarkers for diabetic complications, in particular kidney disease. For these studies she profiles urine samples from large numbers of patients with T1D. Patients at risk could then take dietary precautions or medications to prevent loss of kidney function. More about Dr. Kim

CKing (2).jpg Charles C. King, PhD: Stem Cell Research
Dr. King is an associate research scientist at UC San Diego's Department of Pediatrics. His lab studies the differentiation of human embryonic stem cells into endocrine cells, including insulin-producing cells. Two ongoing projects are 1) to explore the signal transduction pathways that control specific stages of differentiation, and 2) to understand how microRNAs regulate cell fate decisions. More about Dr. King

SPhillips.png Susan Phillips, MD: Obesity/Metabolism Research​/Clinical Research
Dr. Phillips is an assistant clinical professor in the Department of Pediatrics, UC San Diego. Her research involves a translational approach to the study of obesity, specifically looking at fat hormones and their influence on the body's response to insulin. More​ about Dr. Phillips


JShao.png Jianhua Shao, MD, PhD: Inflammation Obesity/Metabolism Research
Dr. Shao is a professor in the Department of Pediatrics at UC San Diego. His research is focuse​d on understanding how maternal metabolism influences the development of obesity and diabetes in offspring.  More​ about Dr. Shao