Dr.Yu, Dr. Diccianni, and Dr. Batova's selected publications:

Dr. Yu's Publications:

Yu AL, Gilman AL, Ozkaynak MF, London WB, Kreissman SG, Chen HX, Smith M, Anderson B, Villablanca JG, Matthay KK, Shimada H, Grupp SA, Seeger R, Reynolds CP, Buxton A, Reisfeld RA, Gillies SD, Cohn SL, Maris JM, Sondel PM, Children's Oncology Group. Anti-GD2 Antibody with GM-CSF, interleukin-2 and Isotretinoin for Neuroblastoma.  N Engl J Med. 2010 Sep 30;363(14):1324-34

Matthay KK, Rani EG. Yu AL. Promising therapeutic targets in neuroblastoma. Clin Cancer Res 18(10) 2740-53, 2012 PMID: 22589483

Chang WW, Lin RJ, Yu J, Chang WY, Fu CH, Lai AC, Yu JC, Yu AL. (2013) The expression and significance of insulin-like growth factor-1 receptor and its pathway on breast cancer stem/progenitors. Breast Cancer Res. 15(3):R39. PMID: 23663564

Huang YL, Hung JT, Cheung SK, Lee HY, Chu KC, Li ST, Lin YC, Ren CT, Cheng TJ, Hsu TL, Yu AL, Wu CY, Wong CH. (2013) Carbohydrate-based vaccines with a glycolipid adjuvant for breast cancer. Proc Natl Acad Sci U S A.  110(7):2517-22.  PMID: 23355685

Kreissman SG, Seeger RC, Matthay KK, London WB, Sposto R, Grupp SA, Haas-Kogan DA, Laquaglia MP, Yu AL, Diller L, Buxton A, Park JR, Cohn SL, Maris JM, Reynolds CP, Villablanca JG. (2013) Purged versus non-purged peripheral blood stem-cell transplantation for high-risk neuroblastoma (COG A3973): a randomized phase 3 trial. Lancet Oncol. 2013 Sep;14(10):999-1008. PMID: 23890779

Terme M, Dorvillius M, Cochonneau D, Chaumette T, Xiao W, Diccianni MB, Barbet J, Yu AL, Paris F, Sorkin LS, Birklé S. Chimeric Antibody c.8B6 to O-Acetyl-GD2 Mediates the Same Efficient Anti-Neuroblastoma Effects as Therapeutic ch14.18 Antibody to GD2 without Antibody Induced Allodynia. PLoS One. 2014 Feb 10;9(2):e87210;

Lin J, Chang YJ, Yang WB, Yu AL, Wong CH. (2014) The multifaceted effects of polysaccharides isolated from Dendrobium huoshanense on immune functions with the induction of interleukin-1 receptor antagonist (IL-1ra) in monocytes. PLoS One. 2014 Apr 4;9(4):e94040. PMID: 24705413

Hung JT, Tsai YC, Lin WD, Jan JT, Lin KH, Huang JR, Cheng JY, Chen MW, Wong CH, Yu AL. (2014) Potent adjuvant effects of novel NKT stimulatory glycolipids on hemagglutinin based DNA vaccine for H5N1 influenza virus. Antiviral Res. 2014 Apr 29;107C:110-118. PMID: 24786174

Fu CH, Lin RJ, Yu J, Chang WW, Liao GS, Chang WY, Tseng LM, Tsai YF, Yu JC, Yu AL.(2014) A novel oncogenic role of inositol phosphatase SHIP2 in ER-Negative breast cancer stem cells: Involvement of JNK/Vimentin activation. Stem Cells. PMID: 24802135

Yu AL, Gilman AL, Ozkaynak MF, Fevzi, M, Sondel, PM, London WB, Cretella, S, Diccianni, M, Cohn SL, Maris JM, Smith, M, Park, Julie on befalf of Children's Oncology Group. Update of Outcome for High-Risk Neuroblastoma Treated on a Randomized Trial of chimeric anti-GD2 antibody (ch14.18) + GM-CSF / IL2 immunotherapy in 1st response: A Children's Oncology Group Study. Advances in Neuroblastoma Research, 2014.

Dr. Diccianni's Publications:

Omura–Minamisawa M, Diccianni MB, Chang RC, Batova A, Bridgeman L, Schiff J, Cohn S, London  WB, Yu AL (2001)  P16 /p14ARF Cell Cycle Regulatory Pathway in Primary Neuroblastoma: p16 Expression is Associated with Advanced Stage Disease.  Clin. Can. Res., 7, 3481-90; PMID: 11705866

You-Chin Lin‡, You-Chin Lin‡, Mitchell B. Diccianni‡, Youngjin Kim, Hsin-Hung Lin, Chien-Hsin Lee, Ruey-Jen Lin, Sang Hoon Joo, Junan Li, Trees-Juan Chuang, An-Suei Yang, Huan-Hsien Kuo, Ming-Daw Tsai, Alice L. Yu (2007) Human p16g, a novel transcriptional variant of p16INK4A, co-expresses with p16INK4A in cancer cells and inhibits cell cycle progression. Oncogene. 26(49):7017-27; PMID: 17486064

Lo, TCT, Barnhill, LM, Kim, Y, Nakae, EA, Yu, AL, Diccianni, MB (2009) Inactivation of SHIP1 in T- cell Acute Lymphoblastic Leukemia due to Mutation and Extensive Alternative Splicing. Leuk Res. 2009 Nov;33(11):1562-6; PMID: 19473701

Lin RJ, Lin YC, Chen J, Kuo HH, Chen YY, Diccianni MB, London WB, Chang CH, Yu AL (2010) microRNA signature and expression of Dicer and Drosha can predict prognosis and delineate risk groups in neuroblastoma. Cancer Res. 70(20):7841-50; PMID: 20805302

Williams RT, Barnhill LM, Kuo HH, Lin WD, Batova A, Yu AL, Diccianni MB. (2014) Chimeras of p14ARF and p16: Functional Hybrids with the Ability to Arrest Growth. PLoS One. 9(2):e88219. PMID: 24505435

Mickaël Terme; Mylène Dorvillius; Denis Cochonneau; Tanguy Chaumette; Wenhua Xiao; Mitchell B. Diccianni; Jacques Barbet; Alice L. Yu; François Paris; Linda L. Sorkin; Stephane Birkle (2014). Chimeric antibody c.8B6 to O-acetyl-GD2 mediates the same efficient anti-neuroblastoma effects than therapeutic ch14.18 antibody to GD2 without antibody induced allodynia. PLoS One. 2014 Feb 10;9 (2):e87210 PMID: 24520328

Barnhill, LM, Williams, RT, Cohen, O, Kim, Y, Batova, A, Mielke, JA, Messer, K, Pu, M, Bao, L, Yu, AL, Diccianni, MB (2014) High expression of CAI2, a 9p21-embedded long non-coding RNA, contributes to advanced stage neuroblastoma. Can Res 74(14):3753-632014. PMID: 25028366

Dr. Batova's Publications:


​Williams, R.T., Yu, A.L., Diccianni, M.B., Theodorakis, E.A., Batova, A. Renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy. Journal of Experimental and Clinical Cancer Research. 32:57, 2013.

Guizzunti G, Theodorakis EA, Yu AL, Zurzolo C, Batova A Cluvenone induces apoptosis via a direct target in mitochondria: a possible mechanism to circumvent chemo-resistance? Invest New Drugs. 30: 1841-8, 2012.

Batova A, Altomare D, Chantarasriwong O, Ohlsen KL, Creek KE, Lin YC, Messersmith A, Yu AL, Yu J, Theodorakis EA.The synthetic caged garcinia xanthone cluvenone induces cell stress and apoptosis and has immune modulatory activity. Mol Cancer Ther. 9: 2869-78, 2010.

Chantarasriwong O, Batova A, Chavasiri W, Theodorakis EA. Chemistry and biology of the caged Garcinia xanthones. Chemistry. 16: 9944-62, 2010.

Batova, A., Shao, L., Diccianni, M.B., Yu, A.L., Tanaka, T., Rephaeli, A., Nudelman, A., and Yu, J.  The histone deacetylase inhibitor AN-9 has selective toxicity to drug-resistant primary leukemia and cancer cell lines.  Blood. 100:  3319-3324, 2002.

Batova, A., Kamps, A., Gillies, S.D., Reisfeld, R.A., and Yu, A.L.  The Ch14.18-GM-CSF fusion protein is effective at mediating antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity in vitro. Clin. Cancer Res. 5: 4259-4263, 1999.

Batova, A., Diccianni, M.B., Yu, J., Bridgeman, L., Pullen, J., Amylon, M.J., and Yu, A.L. Use of alanosine as a methylthioadenosine phosphorylase-selective therapy for T-cell acute lymphoblastic leukemia in vitro. Cancer Res. 59: 1492-1497, 1999.

Batova, A., Diccianni, M.B., Yu, J.C., Nobori, T., Link, M.P., Pullen, J., and Yu, A.L.  Frequent and selective methylation of p15 and deletion of both p15 and p16 in T-cell acute lymphoblastic leukemia (T-ALL). Cancer Res., 57: 832-836, 1997.

Batova, A., Diccianni, M.B., Nobori, T., Vu, T., Bridgeman, L., and Yu, A.L. Frequent deletions in the methylthioadenosine phosphorylase gene in T-cell acute lymphoblastic leukemia: Strategies for enzyme-targeted therapy. Blood. 88: 3083-3090, 1996.